CAS 210245-80-0

Zonampanel

Description:

Zonampanel, identified by its CAS number 210245-80-0, is a chemical compound that belongs to the class of non-competitive antagonists of the AMPA receptor, which is a subtype of glutamate receptors in the central nervous system. This compound has been investigated primarily for its potential therapeutic applications in neurological disorders, particularly in the context of pain management and neuroprotection. Zonampanel exhibits properties that may help modulate excitatory neurotransmission, thereby influencing synaptic plasticity and neuronal excitability. Its chemical structure includes specific functional groups that contribute to its pharmacological activity. The compound has undergone various preclinical and clinical studies to evaluate its efficacy and safety profile. As with many investigational drugs, the full spectrum of its characteristics, including solubility, stability, and metabolic pathways, is subject to ongoing research. Overall, Zonampanel represents a promising avenue in the development of treatments for conditions associated with excessive glutamate activity in the brain.

Formula: C₁₃H₉N₅O₆

InChI: InChI=1S/C13H9N5O6/c19-11(20)5-17-8-4-9(16-2-1-14-6-16)10(18(23)24)3-7(8)15-12(21)13(17)22/h1-4,6H,5H2,(H,15,21)(H,19,20)

InChI key: InChIKey=SPXYHZRWPRQLNS-UHFFFAOYSA-N

SMILES: C(C(O)=O)N1C=2C(=CC(N(=O)=O)=C(C2)N3C=CN=C3)NC(=O)C1=O

Synonyms:

• Zonampanel
• YM 872
• 3,4-Dihydro-7-(1H-imidazol-1-yl)-6-nitro-2,3-dioxo-1(2H)-quinoxalineacetic acid
• 1(2H)-Quinoxalineacetic acid, 3,4-dihydro-7-(1H-imidazol-1-yl)-6-nitro-2,3-dioxo-
• 2-(7-(1H-Imidazol-1-yl)-6-nitro-2,3-dioxo-3,4-dihydroquinoxalin-1(2H)-yl)acetic acid

1(2H)-Quinoxalineacetic acid, 3,4-dihydro-7-(1H-imidazol-1-yl)-6-nitro-2,3-dioxo-

CAS: 210245-80-0

Formula: C₁₃H₉N₅O₆

Purity: 98.06%

Color and Shape: Solid

Molecular weight: 331.2405

Ref: IN-DA002KNV

Zonampanel

CAS: 210245-80-0

Zonampanel is a selective glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist.

Formula: C₁₃H₉N₅O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 331.24

Ref: TM-T17276

(2,3-Dioxo-7-(1H-imidazol-1-yl)-6-nitro-1,2,3,4- tetrahydro-1-quinoxalinyl)acetic acid monohydrate

CAS: 210245-80-0

2,3-Dioxo-7-(1H-imidazol-1-yl)-6-nitro-1,2,3,4-tetrahydroquinoxalinyl)acetic acid monohydrate is an ester of 2,3-dioxohexahydroquinoxaline with acetic acid. It has been shown to have neuroprotective effects in humans suffering from degenerative diseases. The drug has been shown to inhibit the uptake of neurotransmitters in the brain by blocking the organic anion transporters that allow these neurotransmitters to be taken up by cells. 2,3-Dioxohexahydroquinoxaline also blocks ATP channels and prevents neuronal depolarization. This drug may also reduce glomerular filtration rate and prevent renal dysfunction caused by diabetes mellitus.

Formula: C₁₃H₉N₅O₆

Purity: Min. 95%

Molecular weight: 331.24 g/mol

Ref: 3D-KIA24580