CAS 21028-20-6

3-methylcytidine methosulfate

Description:

3-Methylcytidine methosulfate is a chemical compound that belongs to the class of modified nucleosides, specifically a derivative of cytidine. It features a methyl group at the 3-position of the cytidine base, which can influence its biological activity and interactions. The methosulfate group is a sulfonate ester, which enhances the compound's solubility in water and can facilitate its use in biochemical applications. This compound is often utilized in molecular biology, particularly in the synthesis of RNA and in studies involving nucleic acid modifications. Its structural modifications can affect the stability and reactivity of nucleic acids, making it a valuable tool in research focused on gene expression and regulation. Additionally, 3-methylcytidine methosulfate may exhibit unique properties in terms of its interaction with enzymes and other biomolecules, contributing to its utility in various experimental contexts. As with many chemical substances, proper handling and safety precautions are essential due to potential reactivity and biological effects.

Formula: C₁₁H₁₉N₃O₉S

InChI: InChI=1/C10H15N3O5.CH4O4S/c1-12-6(11)2-3-13(10(12)17)9-8(16)7(15)5(4-14)18-9;1-5-6(2,3)4/h2-3,5,7-9,11,14-16H,4H2,1H3;1H3,(H,2,3,4)/t5-,7+,8?,9-;/m1./s1

Cytidine, 3-methyl-, mono(methyl sulfate) (salt) (8CI,9CI)

CAS: 21028-20-6

Formula: C₁₁H₁₉N₃O₉S

Purity: 98%

Color and Shape: Solid

Molecular weight: 369.3483

Ref: IN-DA002KO1

N3-Methylcytidine methosulfate

CAS: 21028-20-6

Ref: 7W-GN9644

3-Methylcytidine methosulfate

CAS: 21028-20-6

3-Methylcytidine (methosulfate), a derivative of cytidine, serves as an internal standard for HPLC and is recognized for its epigenetic modification in tRNA, although its cellular role remains unclear. Research has explored its utility as a cancer biomarker, with findings indicating a notable increase in the urine of breast cancer patients.

Formula: C₁₁H₁₉N₃O₈S

Color and Shape: Solid

Molecular weight: 353.35

Ref: TM-TN7258

3-Methyl Cytidine Methosulfate

Controlled Product

CAS: 21028-20-6

Applications Cytidine derivative.
References Ueda, T., et al.: Chem. Pharmaceut. Bull., 22, 2377 (1974),

Formula: C₁₀H₁₆N₃O₅·CH₃O₄S

Color and Shape: Neat

Molecular weight: 369.35

Ref: TR-M294670

3-Methyl Cytidine-d3 Methosulfate-d3

Controlled Product

CAS: 21028-20-6

Applications Labelled Cytidine derivative.
References Ueda, T., et al.: Chem. Pharmaceut. Bull., 22, 2377 (1974),

Formula: C₁₀D₃H₁₂N₃O₅·CD₃HO₄S

Color and Shape: Neat

Molecular weight: 375.385

Ref: TR-M294672

N3-Methylcytidine methosulfate

CAS: 21028-20-6

N3-Methylcytidine methosulfate is a novel antiviral agent that inhibits the synthesis of DNA and RNA. It has been shown to be effective against hepatitis B virus, herpes simplex virus, varicella-zoster virus, human immunodeficiency virus, and cytomegalovirus. N3-Methylcytidine methosulfate was found to be active in a variety of animal models including mice and rats. This drug has anticancer properties in the treatment of leukemia, lymphoma, and breast cancer. The phosphoramidite derivative of N3-methylcytidine methosulfate is used as an activator for oligonucleotide synthesis.

Formula: C₁₀H₁₅N₃O₅·CH₄SO₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 369.35 g/mol

Ref: 3D-NM02913