CAS 210345-00-9

L-Histidinamide,N-[(phenylmethoxy)carbonyl]-L-tryptophyl-L-a-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-,methyl ester (9CI)

Description:

L-Histidinamide, N-[(phenylmethoxy)carbonyl]-L-tryptophyl-L-a-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester (9CI), with CAS number 210345-00-9, is a synthetic compound characterized by its complex peptide structure. This molecule features multiple amino acid residues, including histidine, tryptophan, and glutamic acid, which contribute to its biological activity and potential therapeutic applications. The presence of a phenylmethoxycarbonyl group suggests that it may be used in drug design to enhance stability or bioavailability. Additionally, the incorporation of a fluorinated moiety indicates potential for increased potency or selectivity in biological interactions. The methyl ester functionality may also influence solubility and permeability, making it relevant for pharmacological studies. Overall, this compound exemplifies the intricate design often employed in peptide-based therapeutics, aiming to optimize efficacy while minimizing side effects. Its specific characteristics, including solubility, stability, and biological activity, would require further empirical investigation to fully understand its potential applications.

Formula: C₃₇H₄₂FN₇O₁₀

Synonyms:

• Caspase-1 Inhibitor Tfa Salt
• Z-Wehd-Fmk-Tfa
• Z-Trp-Glu(Ome)-His-Asp(Ome)-Fmk-Tfa

Z-WEHD-FMK

CAS: 210345-00-9

Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM).

Formula: C₃₇H₄₂FN₇O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 763.78

Ref: TM-TP2161