CAS 21052-18-6

Uridine, 2-thio-, 2',3',5'-tribenzoate

Description:

Uridine, 2-thio-, 2',3',5'-tribenzoate, with the CAS number 21052-18-6, is a modified nucleoside derivative of uridine. This compound features a thio substitution at the 2-position of the uridine base, which can influence its biochemical properties and interactions. The presence of three benzoate groups at the 2', 3', and 5' positions enhances its lipophilicity and may affect its solubility and permeability across biological membranes. As a nucleoside analog, it may exhibit unique pharmacological activities, potentially serving as a substrate for nucleoside transporters or as an inhibitor of nucleic acid synthesis. The structural modifications can also impact its stability and reactivity, making it of interest in medicinal chemistry and biochemistry. Additionally, compounds like this are often studied for their potential therapeutic applications, including antiviral and anticancer properties. Understanding the characteristics of such modified nucleosides is crucial for developing new drugs and exploring their mechanisms of action in biological systems.

Formula: C₃₀H₂₄N₂O₈S

2’,3’,5’-Tri-O-benzoyl-2-thiouridine

CAS: 21052-18-6

Ref: 7W-GN0070

2',3',5'-Tri-O-benzoyl-2-thiouridine

CAS: 21052-18-6

2',3',5'-Tri-O-benzoyl-2-thiouridine is a Nucleoside Derivative - Thio-nucleoside.

Formula: C₃₀H₂₄N₂O₈S

Color and Shape: Solid

Molecular weight: 572.59

Ref: TM-TNU1177

2’,3’,5’-Tri-O-benzoyl-2-thiouridine

Controlled Product

CAS: 21052-18-6

Applications Protected 2-Thiouridine.
References El-Tayeb, A., et al.: J. Med. Chem., 49, 7076 (2006),

Formula: C₃₀H₂₄N₂O₈S

Color and Shape: Neat

Molecular weight: 572.585

Ref: TR-T771500

2',3',5'-Tri-O-benzoyl-2-thiouridine

CAS: 21052-18-6

2',3',5'-Tri-O-benzoyl-2-thiouridine is an analog of the nucleoside thiouracil, which is a modified nucleoside. It inhibits the synthesis of DNA and RNA by competitively inhibiting the enzyme thymidylate synthase. 2',3',5'-Tri-O-benzoyl-2-thouridine has been shown to exhibit anticancer activity in vitro and in vivo. This compound also exhibits antiviral properties against herpes simplex virus type 1 (HSV1) and Herpes simplex virus type 2 (HSV2).

Formula: C₃₀H₂₄N₂O₈S

Purity: Min. 95%

Molecular weight: 572.59 g/mol

Ref: 3D-NT16569