CAS 2108100-73-6

(2E,4E)-N-[2-(3,4-Dimethoxyphenyl)ethyl]dodeca-2,4-dienamide

CAS: 2108100-73-6

2,4-Dienamide is a potent and selective inhibitor of the Kv1.3 voltage-gated potassium channel. It binds to the Cys-loop receptor and prevents ion flow through the channel. This inhibition has been shown to suppress inflammatory responses in mouse models of colitis, arthritis, and asthma. 2,4-Dienamide has also been shown to be an activator for G protein coupled receptors (GPCRs), leading to increased intracellular calcium levels in cells. The effects of 2,4-dienamide on receptor function can be inhibited by peptides that bind to the same site as 2,4-dienamide as well as by antibodies against the ligand binding domain of Kv1.3 channels.

Formula: C₂₂H₃₃NO₃

Purity: Min. 95%

Molecular weight: 359.5 g/mol

Ref: 3D-IJD10073

WOBE437

CAS: 2108100-73-6

WOBE437 is a selective endocannabinoid reuptake inhibitor which reduces disease progression in a mouse model of multiple sclerosis

Formula: C₂₂H₃₃NO₃

Color and Shape: Solid

Molecular weight: 359.5

Ref: TM-T69899