CAS 2113650-04-5

BMS-1001 hydrochloride

CAS: 2113650-04-5

BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect

Formula: C₃₅H₃₅ClN₂O₇

Purity: 97.36%

Color and Shape: Solid

Molecular weight: 631.11

Ref: TM-T10565

N-[[2-[(3-Cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]-5-methylphenyl]methyl]-D-serine hydrochloride

CAS: 2113650-04-5

Formula: C₃₅H₃₅ClN₂O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 631.1146

Ref: IN-DA01LITV

BMS-1001 hydrochloride

CAS: 2113650-04-5

BMS-1001 hydrochloride

Purity: ≥95%

Molecular weight: 631.11g/mol

Ref: 54-BUP07047

BMS-1001 hydrochloride

CAS: 2113650-04-5

BMS-1001 hydrochloride is a peptide that is an activator of ion channels. It has been shown to inhibit the activation of potassium channels and calcium channels in rat brain slices. BMS-1001 hydrochloride also binds to the receptor site of human calcitonin gene-related peptide (CGRP) and blocks its binding to CGRP receptor sites on mast cells. This prevents the release of histamine, which is responsible for allergic reactions such as hay fever, asthma, and chronic urticaria.
BMS-1001 hydrochloride has been shown to be a potent inhibitor of protein interactions with ligands and receptors. It inhibits the interaction between human erythropoietin (EPO) and its receptor by competing with endogenous EPO for binding sites on the surface of erythrocytes.

Formula: C₃₅H₃₅ClN₂O₇

Purity: Min. 95%

Molecular weight: 631.1 g/mol

Ref: 3D-NJD65004