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CAS 211426-18-5

:

Interphotoreceptor Retinoid Binding Protein Fragment IRBP

Description:
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) is a protein fragment derived from the larger interphotoreceptor retinoid binding protein, which plays a crucial role in the visual cycle by facilitating the transport of retinoids between photoreceptors and the retinal pigment epithelium. The CAS number 211426-18-5 identifies this specific fragment, which is characterized by its ability to bind retinoids, thus influencing visual processes. IRBP is primarily composed of multiple repeating units that contribute to its structural stability and functional properties. It is soluble in aqueous environments and exhibits a high affinity for retinoids, which are essential for the regeneration of visual pigments. The fragment's molecular interactions are vital for maintaining the health of photoreceptor cells and supporting visual signal transduction. Additionally, IRBP has been studied for its potential implications in retinal diseases, making it a subject of interest in biomedical research. Overall, IRBP is an essential component in the complex biochemical pathways involved in vision.
Formula:C103H157N25O29
Synonyms:
  • L-Aspartic acid, L-serylglycyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-isoleucyl-L-seryl-L-tyrosyl-L-leucyl-L-histidyl-L-prolylglycyl-L-asparaginyl-L-threonyl-L-isoleucyl-L-leucyl-L-histidyl-L-valyl-
  • Interphotoreceptor Retinoid Binding Protein Fragment IRBP
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Found 2 products.
  • Interphotoreceptor Retinoid Binding Protein Fragment (IRBP)

    CAS:
    IRBP Fragment is a 20-residue peptide in IRBP 161-180, causing post-uveitis (EAU).
    Formula:C103H157N25O29
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2209.5
  • IRBP (161-180)

    CAS:
    <p>IRBP (161-180) derived from the interphotoreceptor retinoid-binding protein (IRBP), present in the interphotoreceptor matrix and is expressed by cone and rod photoreceptors in the eye. IRBP is involved in retinoid delivery and protects retinal cells from oxidative stress.In retinitis pigmentosa patients, IRBP can be subjected to mutations resulting in a non-secreted form of IRBP to be produced. Furthermore IRBP gene mutations have been associated with high myopia and retinal dystrophy.The expression of IRBP is reduced in diabetes patients which may lead to visual cycle misfunction and the photoreceptors can be vulnerable to damage.</p>
    Formula:C103H157N25O29
    Color and Shape:Powder
    Molecular weight:2,209.5 g/mol

    Ref: 3D-CRB1001412

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    500µg
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