CAS 21150-22-1

B-amanitin from amanita phalloides

Description:

B-amanitin is a cyclic peptide and a potent toxin primarily derived from the mushroom Amanita phalloides, commonly known as the death cap mushroom. It is classified as an amatoxin, which is known for its high toxicity and ability to inhibit RNA polymerase II, leading to the disruption of mRNA synthesis in eukaryotic cells. This inhibition results in severe liver and kidney damage, making B-amanitin a significant cause of mushroom poisoning. The structure of B-amanitin consists of eight amino acids arranged in a specific cyclic configuration, contributing to its stability and biological activity. It is soluble in water and exhibits a relatively high molecular weight. Due to its toxicity, B-amanitin has been the subject of extensive research, particularly in the fields of pharmacology and toxicology, as well as its potential therapeutic applications in cancer treatment. Safety precautions are essential when handling this compound, given its lethal effects even in small doses.

Formula: C₃₉H₅₃N₉O₁₅S

InChI: InChI=1/C39H53N9O15S/c1-4-16(2)31-36(60)41-11-28(53)42-25-15-64(63)38-21(20-6-5-18(50)7-22(20)45-38)9-23(33(57)40-12-29(54)46-31)43-37(61)32(17(3)27(52)14-49)47-35(59)26-8-19(51)13-48(26)39(62)24(10-30(55)56)44-34(25)58/h5-7,16-17,19,23-27,31-32,45,49-52H,4,8-15H2,1-3H3,(H,40,57)(H,41,60)(H,42,53)(H,43,61)(H,44,58)(H,46,54)(H,47,59)(H,55,56)/t16?,17?,19?,23-,24-,25-,26-,27-,31-,32-,64+/m0/s1

Synonyms:

• -Amanitine

β-Amanitin

CAS: 21150-22-1

Formula: C₃₉H₅₃N₉O₁₅S

Molecular weight: 919.95

Ref: 7W-GK3114

β-Amanitin from Amanita Phalloides

CAS: 21150-22-1

β-Amanitin from Amanita Phalloides

Formula: C₃₉H₅₃N₉O₁₅S

Purity: By hplc: >90% (Typical Value in Batch COA)

Color and Shape: White To Off White Solid

Molecular weight: 919.95g/mol

Ref: 54-BIA0311

β-Amanitin

CAS: 21150-22-1

β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom, and inhibits inhibits eukaryotic RNA polymerase II and III.

Formula: C₃₉H₅₃N₉O₁₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 919.96

Ref: TM-T13474

b-Amanitin

CAS: 21150-22-1

Cyclic peptide; inhibitor of eukaryotic RNA polymerase II and III

Formula: C₃₉H₅₃N₉O₁₅S

Purity: Min. 90 Area-%

Color and Shape: Powder

Molecular weight: 919.96 g/mol

Ref: 3D-FA57612