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CAS 211690-33-4

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Lomefloxacin aspartate

Description:
Lomefloxacin aspartate is a synthetic antibacterial agent belonging to the fluoroquinolone class of antibiotics. It is primarily used for the treatment of various bacterial infections due to its broad-spectrum activity against both Gram-positive and Gram-negative bacteria. The compound exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription. Lomefloxacin aspartate is characterized by its solubility in water, which enhances its bioavailability when administered. The substance is typically formulated as a salt, which can improve its stability and absorption profile. Commonly, it is utilized in the treatment of urinary tract infections and respiratory tract infections. As with other fluoroquinolones, it may have side effects, including gastrointestinal disturbances and potential effects on tendon health. Caution is advised in its use among certain populations, such as pregnant women and those with a history of tendon disorders. Overall, Lomefloxacin aspartate represents a valuable option in the antibiotic arsenal, particularly for specific bacterial infections.
Formula:C17H19F2N3O3·C4H7NO4
InChI:InChI=1S/C17H19F2N3O3.C4H7NO4/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22;5-2(4(8)9)1-3(6)7/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25);2H,1,5H2,(H,6,7)(H,8,9)/t;2-/m.0/s1
SMILES:CCn1cc(c(=O)c2cc(c(c(c12)F)N1CCNC(C)C1)F)C(=O)O.C([C@@H](C(=O)O)N)C(=O)O
Synonyms:
  • 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid L-Aspartate
  • 1-Ethyl-6,8-difluoro-7-(3-Methyl-1-piperazinyl)-4-oxo-1,4 -dihydro-3-quinoline carboxylic Acid L-Aspartate
  • DM 10 L-Aspartate
  • SC 47111A L-Aspartate
  • (S)-2-Aminosuccinic acid 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (1:1)
  • Lomefloxacin aspartate
  • Lomefloxacin, aspartate
  • (S)-2-Aminosuccinic acid 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquin
  • 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
  • (S)-2-Aminosuccinic acid 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoli
  • See more synonyms
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