CAS 21187-98-4: Gliclazide
Description:Gliclazide is an oral hypoglycemic agent belonging to the sulfonylurea class, primarily used in the management of type 2 diabetes mellitus. It functions by stimulating insulin secretion from the pancreatic beta cells, thereby lowering blood glucose levels. Gliclazide has a moderate duration of action and is often administered once or twice daily, depending on the patient's needs. The chemical structure of gliclazide includes a sulfonylurea moiety, which is essential for its pharmacological activity. It is typically well-absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within a few hours after ingestion. Gliclazide is metabolized in the liver and excreted primarily through the urine. Common side effects may include hypoglycemia, gastrointestinal disturbances, and weight gain. It is important for patients to monitor their blood glucose levels regularly while on gliclazide therapy and to adhere to dietary recommendations. As with any medication, it is crucial to consult healthcare professionals for personalized advice and management.
Formula:C15H21N3O3S
InChI:InChI=1S/C15H21N3O3S/c1-11-5-7-14(8-6-11)22(20,21)17-15(19)16-18-9-12-3-2-4-13(12)10-18/h5-8,12-13H,2-4,9-10H2,1H3,(H2,16,17,19)
InChI key:InChIKey=BOVGTQGAOIONJV-UHFFFAOYSA-N
SMILES:O=C(NN1CC2CCCC2C1)NS(=O)(=O)C3=CC=C(C=C3)C
- Synonyms:
- 1-(3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea
- 1-(4-Methylbenzenesulfonyl)-3-[octahydrocyclopenta[c]pyrrol-2-yl]urea
- 1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea
- Cyclopenta[c]pyrrole, benzenesulfonamide deriv.
- Diabezidum
- Diabrezide
- Diabyl
- Diamicron
- Diaprel
- Gliclazid
- See more synonyms
- Gliclazida
- Gliclazide
- Glimicron
- Glinormax
- Glyzide
- N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea
- N-[[(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methylbenzenesulfonamide
- S 1702
- S 852
- Se 1702
- Urea, 1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)-
- Benzenesulfonamide, N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-