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CAS 2119-75-7

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Fluperolone acetate

Description:
Fluperolone acetate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is primarily used in dermatological formulations to treat various skin conditions, including eczema and dermatitis. The compound exhibits a high affinity for glucocorticoid receptors, which contributes to its effectiveness in reducing inflammation and modulating immune responses. Fluperolone acetate is characterized by its ability to penetrate the skin barrier, allowing for localized therapeutic effects with minimal systemic absorption. Its chemical structure includes a fluorinated steroid backbone, which enhances its potency and stability compared to non-fluorinated corticosteroids. The substance is typically formulated in topical preparations, such as creams or ointments, and is administered externally. Safety and efficacy profiles indicate that, while generally well-tolerated, prolonged use may lead to potential side effects, including skin atrophy or systemic effects if absorbed in significant amounts. As with any corticosteroid, it is essential to use Fluperolone acetate under medical supervision to mitigate risks and ensure appropriate therapeutic outcomes.
Formula:C24H31FO6
InChI:InChI=1/C24H31FO6/c1-13(31-14(2)26)20(29)23(30)10-8-17-18-6-5-15-11-16(27)7-9-21(15,3)24(18,25)19(28)12-22(17,23)4/h7,9,11,13,17-19,28,30H,5-6,8,10,12H2,1-4H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1
InChI key:InChIKey=HHPZZKDXAFJLOH-QZIXMDIESA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C([C@@H](OC(C)=O)C)=O)(O)CC3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Synonyms:
  • (11β,17α)-17-[(2S)-2-(Acetyloxy)-1-oxopropyl]-9-fluoro-11,17-dihydroxyandrosta-1,4-dien-3-one
  • (2S)-1-[(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-1-oxopropan-2-yl acetate (non-preferred name)
  • 17(S)-[α-(Acetyloxy)-1-oxopropyl]-9-fluoro-11β,17α-dihydroxyandrosta-1,4-dien-3-one
  • 17β-[2-Acetoxypropionyl]-9α-fluoro-11β,17-dihydroxyandrosta-1,4-dien-3-one
  • 21-Methyl-9α-fluoroprednisolone acetate
  • 9-Fluoro-11beta,17alpha-dihydroxy-17-(S)-lactoylandrosta-1,4-dien-3-one 17beta-acetate
  • 9-Fluoro-11beta,17alpha-hydroxy-17-lactoylandrosta-1,4-diene 17beta-acetate
  • 9α-Fluoro-11β,17α,21-trihydroxy-21-methylpregna-1,4-diene-3,20-dione 21-acetate
  • Alacortril
  • Androsta-1,4-dien-3-one, 17-(2-(acetyloxy)-1-oxopropyl)-9-fluoro-11,17-dihydroxy-, (11beta,17alpha,17(S))-
  • See more synonyms
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Found 3 products.
  • Fluperolone Acetate
    TRC
    + Info

    Fluperolone Acetate

    Controlled Product
    CAS:
    Formula:C24H31FO6
    Color and Shape:Neat
    Molecular weight:434.498

    Ref: TR-F598150

    100mg
    17,136.00€
  • Fluperolone acetate
    Biosynth
    + Info

    Fluperolone acetate

    Controlled Product
    CAS:
    <p>Fluperolone acetate is a synthetic steroid that has been used as an anti-inflammatory agent. It is a potent corticosteroid and has been shown to inhibit the growth of microorganisms, such as bacteria and fungi. Fluperolone acetate does not cross the blood-brain barrier into the central nervous system, so it can be used for the treatment of inflammatory diseases in the eye without affecting vision. This drug also has been shown to reduce choroidal neovascularization in patients with age-related macular degeneration. Some biodegradable implants have been made from fluoropolymers, which are biocompatible polymers that are degraded by hydrolysis or enzymatic action in vivo. These implants may provide a sealant for use in surgical procedures and for treating cavities.</p>
    Formula:C24H31FO6
    Purity:Min. 95%
    Molecular weight:434.5 g/mol

    Ref: 3D-FF23501

    2mg
    To inquire
    5mg
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    10mg
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    25mg
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    50mg
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  • Fluperolone acetate
    Targetmol
    + Info

    Fluperolone acetate

    CAS:
    <p>Fluperolone acetate is a Glucocorticoid/Adrenal Cortex Hormone.</p>
    Formula:C24H31FO6
    Color and Shape:Solid
    Molecular weight:434.50

    Ref: TM-T31826

    25mg
    2,300.00€
    50mg
    3,022.00€
    100mg
    4,085.00€