CAS 21200-24-8
:Indolmycin
Description:
Indolmycin is a naturally occurring antibiotic that belongs to the class of indole derivatives. It is primarily known for its antibacterial properties, particularly against Gram-positive bacteria. The compound exhibits a unique mechanism of action by inhibiting tryptophan synthetase, an enzyme crucial for the biosynthesis of the amino acid tryptophan. This inhibition disrupts protein synthesis and cellular metabolism in susceptible bacteria. Indolmycin is characterized by its complex molecular structure, which includes an indole ring, contributing to its biological activity. It is typically isolated from microbial sources, particularly from certain strains of Streptomyces. In addition to its antibacterial effects, research has indicated potential applications in cancer therapy due to its ability to interfere with cellular processes. However, its clinical use is limited, and further studies are necessary to fully understand its pharmacological properties and potential therapeutic applications. As with many antibiotics, resistance can develop, necessitating careful consideration in its use.
Formula:C14H15N3O2
InChI:InChI=1S/C14H15N3O2/c1-8(12-13(18)17-14(15-2)19-12)10-7-16-11-6-4-3-5-9(10)11/h3-8,12,16H,1-2H3,(H,15,17,18)/t8-,12+/m1/s1
InChI key:InChIKey=GNTVWGDQPXCYBV-PELKAZGASA-N
SMILES:[C@@H](C)(C=1C=2C(NC1)=CC=CC2)[C@@]3(OC(NC)=NC3=O)[H]
Synonyms:- (5S)-5-[(1R)-1-(1H-Indol-3-yl)ethyl]-2-(methylamino)-4(5H)-oxazolone
- (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one
- 2-Methylamino-5α-(β-indolyl)ethyl-2-oxazolin-4-one
- 2-Oxazolin-4-one, 5-(1-indol-3-ylethyl)-2-(methylamino)-, (1R,5S)-
- 4(5H)-Oxazolone, 5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-, (5S)-
- 4(5H)-Oxazolone, 5-[1-(1H-indol-3-yl)ethyl]-2-(methylamino)-, [S-(R*,S*)]-
- 5-(1-Indol-3-ylethyl)-2-(methylamino)-2-oxazolin-4-one
- Indolemycin
- Indolmycin
- Pa-155A
- Tak-083
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