CAS 21203-86-1

2-Phenyl-4-pyridinamine

Description:

2-Phenyl-4-pyridinamine, also known by its CAS number 21203-86-1, is an organic compound characterized by its structure, which features a pyridine ring substituted with an amino group and a phenyl group. This compound typically appears as a solid and is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The presence of the amino group contributes to its basicity and reactivity, allowing it to participate in various chemical reactions, such as nucleophilic substitutions. Additionally, the phenyl group enhances its lipophilicity, which can influence its bioavailability and interaction with biological targets. 2-Phenyl-4-pyridinamine may exhibit various biological activities, making it of interest in research related to drug discovery. Its solubility and stability can vary depending on the solvent and environmental conditions, which are important factors to consider in practical applications. Overall, this compound represents a significant structure in the field of organic and medicinal chemistry.

Formula: C₁₁H₁₀N₂

InChI: InChI=1S/C11H10N2/c12-10-6-7-13-11(8-10)9-4-2-1-3-5-9/h1-8H,(H2,12,13)

InChI key: InChIKey=CHVKPWIABFICLK-UHFFFAOYSA-N

SMILES: NC=1C=C(N=CC1)C2=CC=CC=C2

Synonyms:

• 2-Phenyl-4-aminopyridine
• 2-Phenyl-4-pyridinamine
• 2-Phenyl-pyridin-4-ylamine
• 4-Pyridinamine, 2-Phenyl-
• Pyridine, 4-amino-2-phenyl-
• 2-Phenylpyridin-4-amine

2-Phenylpyridin-4-amine

CAS: 21203-86-1

Formula: C₁₁H₁₀N₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 170.2105

Ref: IN-DA0037T4

4-Amino-2-phenylpyridine

CAS: 21203-86-1

4-Amino-2-phenylpyridine

Formula: C₁₁H₁₀N₂

Purity: 98%

Color and Shape: pale yellow solid

Molecular weight: 170.21g/mol

Ref: 54-OR471657

4-Amino-2-phenylpyridine

CAS: 21203-86-1

Formula: C₁₁H₁₀N₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 170.215

Ref: 10-F079760

2-PPA

CAS: 21203-86-1

2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 μM), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.

Formula: C₁₁H₁₀N₂

Color and Shape: Solid

Molecular weight: 170.21

Ref: TM-T89916