CAS 212141-54-3: Vatalanib

Description: Vatalanib, with the CAS number 212141-54-3, is a small molecule that functions primarily as a tyrosine kinase inhibitor. It is designed to target and inhibit various receptor tyrosine kinases, which play a crucial role in processes such as cell proliferation, angiogenesis, and tumor growth. Vatalanib has shown potential in the treatment of various cancers by disrupting the signaling pathways that promote tumor development and metastasis. The compound is characterized by its ability to interfere with vascular endothelial growth factor (VEGF) signaling, thereby inhibiting angiogenesis, which is essential for tumor survival and growth. In terms of its chemical structure, Vatalanib contains specific functional groups that contribute to its biological activity and pharmacokinetic properties. The compound has been the subject of research in clinical trials, exploring its efficacy and safety in cancer therapy. As with many targeted therapies, the effectiveness of Vatalanib may vary based on the specific cancer type and the molecular characteristics of the tumor.

Formula: C₂₀H₁₅ClN₄

InChI: InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)

InChI key: InChIKey=YCOYDOIWSSHVCK-UHFFFAOYSA-N

SMILES: ClC1=CC=C(C=C1)NC2=NN=C(C=3C=CC=CC23)CC=4C=CN=CC4

Synonyms:

• 1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-
• Cgp 79787
• N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
• N-(4-Chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
• Pynasunate
• Vatalanib
• Vatalinib

1-Phthalazinamine,N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-

CAS: 212141-54-3

• Formula: C₂₀H₁₅ClN₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 346.8129

Vatalanib hydrochloride

CAS: 212141-54-3

• Formula: C₂₀H₁₆Cl₂N₄
• Molecular weight: 383.27

Vatalanib free base

CAS: 212141-54-3

Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).

• Formula: C₂₀H₁₅ClN₄
• Purity: 99.52%
• Color and Shape: Solid
• Molecular weight: 346.81

Vatalanib

CAS: 212141-54-3

• Molecular weight: 346.81g/mol

Vatalanib HCl

CAS: 212141-54-3

VEGFR tyrosine kinase inhibitor

• Formula: C₂₀H₁₅ClN₄•HCl
• Purity: Min. 95%
• Molecular weight: 383.27 g/mol

Vatalanib

CAS: 212141-54-3

Vatalanib is a new anti-cancer drug that has been developed to inhibit the production of …

• Formula: C₂₀H₁₅ClN₄
• Purity: Min. 95%
• Molecular weight: 346.8 g/mol

VATALANIB BASE

CAS: 212141-54-3

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 346.82000732421875