CAS 212142-18-2: Vatalanib succinate

Description: Vatalanib succinate, with the CAS number 212142-18-2, is a small molecule that functions primarily as a tyrosine kinase inhibitor. It is designed to target specific receptors involved in angiogenesis, particularly the vascular endothelial growth factor (VEGF) receptors, which play a crucial role in tumor growth and metastasis. This compound is characterized by its ability to inhibit tumor vascularization, thereby potentially limiting the growth of various cancers. Vatalanib succinate is typically administered in a pharmaceutical formulation, often as a salt to enhance its solubility and bioavailability. The substance exhibits a moderate to high affinity for its target receptors, which contributes to its therapeutic efficacy. Additionally, it is important to consider its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, which influence its overall effectiveness and safety profile in clinical settings. As with many targeted therapies, ongoing research continues to explore its potential applications and optimize its use in cancer treatment.

Formula: C₂₀H₁₅ClN₄·C₄H₆O₄

InChI: InChI=1S/C20H15ClN4.C4H6O4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;5-3(6)1-2-4(7)8/h1-12H,13H2,(H,23,25);1-2H2,(H,5,6)(H,7,8)

InChI key: InChIKey=LLDWLPRYLVPDTG-UHFFFAOYSA-N

SMILES: O=C(O)CCC(=O)O.ClC1=CC=C(C=C1)NC2=NN=C(C=3C=CC=CC23)CC=4C=CN=CC4

Synonyms:

• 1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, butanedioate (1:1)
• Butanedioic acid, compd. with N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine (1:1)
• Cgp 79787D
• N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine butanedioate
• N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine butanedioate (1:1)
• Ptk 787
• Ptk 787/Zk 222584
• Ptk 787Zk22258
• Zk 222584

Butanedioic acid, compd. withN-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine (1:1)OTHER CA INDEX NAMES:1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-,butanedioate (1:1)

CAS: 212142-18-2

• Formula: C₂₄H₂₁ClN₄O₄
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 464.9009

Vatalanib Succinate

CAS: 212142-18-2

• Formula: C₂₀H₁₅ClN₄·C₄H₆O₄
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow to Light orange powder to crystal
• Molecular weight: 464.91

Vatalanib succinate

CAS: 212142-18-2

Vatalanib succinate is a VEGFR, PDGFR-β, c-Kit, c-Fms, and aromatase inhibitor.

• Formula: C₂₄H₂₁ClN₄O₄
• Color and Shape: Liquid
• Molecular weight: 464.91

Vatalanib succinate

CAS: 212142-18-2

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• Formula: C₂₄H₂₁ClN₄O₄
• Purity: Min. 95%
• Molecular weight: 464.9 g/mol