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CAS 2121513-63-9

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3-Chloro-6-fluoro-2-methoxyphenylboronic acid pinacol ester

Description:
3-Chloro-6-fluoro-2-methoxyphenylboronic acid pinacol ester is a boronic acid derivative characterized by the presence of a boron atom bonded to a phenyl ring that features both a chlorine and a fluorine substituent, as well as a methoxy group. This compound is typically utilized in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling, which is essential for forming carbon-carbon bonds. The pinacol ester moiety enhances the stability and solubility of the boronic acid, making it more amenable to various synthetic applications. The presence of halogen atoms (chlorine and fluorine) can influence the electronic properties of the molecule, potentially affecting its reactivity and interaction with other reagents. Additionally, the methoxy group can serve as an electron-donating substituent, further modulating the compound's reactivity. Overall, this compound is valuable in the development of pharmaceuticals and agrochemicals, contributing to the synthesis of complex organic molecules.
Formula:C13H17BClFO3
Synonyms:
  • 3-Chloro-6-fluoro-2-methoxyphenylboronic acid pinacol ester
  • 2-(3-Chloro-6-fluoro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 1,3,2-Dioxaborolane, 2-(3-chloro-6-fluoro-2-methoxyphenyl)-4,4,5,5-tetramethyl-
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