CAS 2121989-91-9

GSK2850163

CAS: 2121989-91-9

GSK2850163

Purity: ≥98%

Molecular weight: 446.41g/mol

Ref: 54-BUP13576

GSK2850163

CAS: 2121989-91-9

GSK2850163 is a small-molecule inhibitor, which is derived synthetically. It functions by selectively targeting bromodomains, which are protein interaction modules that recognize acetylated lysine residues. This action disrupts the interaction between bromodomains and acetylated histones, thereby influencing gene expression. Such selective targeting allows for modulation of transcriptional programs that can be aberrant in various diseases.

Formula: C₂₄H₂₉Cl₂N₃O

Purity: Min. 95%

Molecular weight: 446.4 g/mol

Ref: 3D-WJD98991

GSK2850163

CAS: 2121989-91-9

GSK2850163 is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit RNase activity and IRE1α kinase activity (IC50s: 200 and 20 nM).

Formula: C₂₄H₂₉Cl₂N₃O

Purity: 99.04%

Color and Shape: Solid

Molecular weight: 446.41

Ref: TM-T11488