CAS 212370-59-7

L-Cysteinamide,N-acetyl-L-cysteinyl-L-norleucyl-L-arginyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophylglycyl-,cyclic (1®9)-disulfide

Description:

L-Cysteinamide, N-acetyl-L-cysteinyl-L-norleucyl-L-arginyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophylglycyl-, cyclic (1®9)-disulfide, identified by CAS number 212370-59-7, is a complex peptide compound characterized by its cyclic structure and disulfide bond formation. This compound features a sequence of amino acids, including cysteine, arginine, histidine, tryptophan, and others, which contribute to its unique properties and biological activity. The presence of the cyclic disulfide linkage enhances its stability and may influence its interaction with biological targets, potentially affecting its pharmacological profile. The incorporation of aromatic and hydrophobic residues, such as naphthalene and norleucine, suggests that the compound may exhibit specific binding affinities or biological functions. Additionally, the N-acetyl modification can impact solubility and bioavailability. Overall, this compound's intricate structure and modifications make it a subject of interest in biochemical research, particularly in the fields of drug design and peptide therapeutics.

Formula: C₅₈H₇₉N₁₉O₁₀S₂

Synonyms:

• Hs024

Acetyl-(Cys³,Nle⁴,Arg⁵,D-2-Nal⁷,Cys¹¹)-α-MSH (3-11) amide

CAS: 212370-59-7

The cyclic MSH analog HS024 showed about 20-fold selectivity and very high affinity (Ki = 0.29 nM) for the melanocortin-4 (MC4) receptor and also increased the food intake, indicating that blockade of the MC4 receptor is a highly effective way to increase feeding.

Formula: C₅₈H₇₉N₁₉O₁₀S₂

Purity: 97.4%

Color and Shape: White Lyophilisate

Molecular weight: 1266.52

Ref: 01-4029134

HS024

CAS: 212370-59-7

HS024

Purity: ≥98%

Molecular weight: 1266.5g/mol

Ref: 54-BUP04376

HS024

CAS: 212370-59-7

HS024 is a highly potent melanocortin MC4 receptor antagonist, increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats.

Formula: C₅₈H₇₉N₁₉O₁₀S₂

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 1266.5

Ref: TM-TP1898

Ac-Cys-Nle-Arg-His-D-2-Nal-Arg-Trp-Gly-Cys-NH2

CAS: 212370-59-7

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Formula: C₅₈H₇₉N₁₉O₁₀S₂

Purity: Min. 95%

Molecular weight: 1,266.5 g/mol

Ref: 3D-FA109313