CAS 2127-01-7

clorexolone

Description:

Clorexolone, with the CAS number 2127-01-7, is a synthetic compound primarily used in dermatological applications. It is classified as a topical anti-inflammatory and antiseptic agent, often utilized in formulations for treating skin conditions such as eczema and psoriasis. Clorexolone exhibits properties that help reduce inflammation and promote healing, making it beneficial in various therapeutic contexts. The compound is typically presented in cream or ointment forms, allowing for localized application. Its mechanism of action involves modulating immune responses and inhibiting the proliferation of certain skin cells, which contributes to its effectiveness in managing inflammatory skin disorders. Clorexolone is generally well-tolerated, but like any medication, it may have potential side effects, including skin irritation or allergic reactions in sensitive individuals. Overall, clorexolone serves as a valuable option in dermatological therapy, providing relief from symptoms associated with various skin ailments.

Formula: C₁₄H₁₇ClN₂O₃S

InChI: InChI=1/C14H17ClN2O3S/c15-12-6-9-8-17(10-4-2-1-3-5-10)14(18)11(9)7-13(12)21(16,19)20/h6-7,10H,1-5,8H2,(H2,16,19,20)

InChI key: InChIKey=VPMWFZKOWULPGT-UHFFFAOYSA-N

SMILES: O=C1C=2C(CN1C3CCCCC3)=CC(Cl)=C(S(N)(=O)=O)C2

Synonyms:

• 12833 R.P.
• 1H-Isoindole-5-sulfonamide, 2,3-dihydro-6-chloro-2-cyclohexyl-3-oxo-
• 1H-Isoindole-5-sulfonamide, 6-chloro-2-cyclohexyl-2,3-dihydro-3-oxo-
• 5-Chloro-2-cyclohexyl-1-oxo-6-sulfamoylisoindoline
• 5-Chloro-2-cyclohexyl-1-oxo-6-sulphamoylisoindoline
• 5-Isoindolinesulfonamide, 6-chloro-2-cyclohexyl-3-oxo-
• 6-Chloro-2-cyclohexyl-2,3-dihydro-3-oxo-1H-isoindole-5-sulfonamide
• 6-Chloro-2-cyclohexyl-3-oxo-5-isoindolinesulfonamide
• 6-chloro-2-cyclohexyl-3-oxo-2,3-dihydro-1H-isoindole-5-sulfonamide
• Brn 0493411
• Chlorexolone
• Cloresolone
• Cloresolone [DCIT]
• Clorexolon
• Clorexolona
• Clorexolona [INN-Spanish]
• Clorexolone [USAN:INN:BAN]
• Clorexolonum
• Clorexolonum [INN-Latin]
• Flonatril
• Klorex
• M & B 8430
• M. and B. 8430
• Nefrolan
• Rp 12833
• Unii-Q2Plt3Fs05
• 5-22-07-00591 (Beilstein Handbook Reference)
• Clorexolone
• clorexolone USP/EP/BP
• 12833 RP
• 6-chloro-2-cyclohexyl-3-keto-isoindoline-5-sulfonamide

Clorexolone

CAS: 2127-01-7

Clorexolone is a low-ceiling sulfonamide diuretic.

Formula: C₁₄H₁₇ClN₂O₃S

Color and Shape: Solid

Molecular weight: 328.81

Ref: TM-T30983

Chlorexolone

Controlled Product

CAS: 2127-01-7

Applications Chlorexolone is a low-ceiling sulfonamide diuretic.
References Goebel, C., et al.: Anal. Chimica Acta, 502, 65 (2004); Smith, E., et al.: J. Chromat., 384, 259 (1987)

Formula: C₁₄H₁₇ClN₂O₃S

Color and Shape: Neat

Molecular weight: 328.81

Ref: TR-C327080

Chlorexolone-d11

Controlled Product

CAS: 2127-01-7

Formula: C₁₄₂H₁₁H₆ClN₂O₃S

Color and Shape: Neat

Molecular weight: 339.882

Ref: TR-C327082