CAS 213027-19-1

Cipralisant

Description:

Cipralisant, identified by the CAS number 213027-19-1, is a novel chemical compound primarily investigated for its potential applications in the treatment of sleep disorders, particularly insomnia. It functions as a selective antagonist of the orexin receptors, which play a crucial role in regulating wakefulness and arousal. By inhibiting these receptors, Cipralisant promotes sleep and may help in managing conditions characterized by excessive wakefulness. The compound has been studied for its pharmacological properties, including its efficacy, safety profile, and side effects. In preclinical and clinical trials, Cipralisant has shown promise in improving sleep quality without the typical side effects associated with traditional sedatives. Its unique mechanism of action distinguishes it from other sleep aids, making it a subject of interest in sleep medicine research. As with any investigational drug, ongoing studies are essential to fully understand its therapeutic potential and long-term effects.

Formula: C₁₄H₂₀N₂

InChI: InChI=1S/C14H20N2/c1-14(2,3)7-5-4-6-11-8-12(11)13-9-15-10-16-13/h9-12H,5,7-8H2,1-3H3,(H,15,16)/t11-,12-/m1/s1

InChI key: InChIKey=CVKJAXCQPFOAIN-VXGBXAGGSA-N

SMILES: C(#CCCC(C)(C)C)[C@H]1[C@@H](C1)C2=CN=CN2

Synonyms:

• 1H-Imidazole, 4-[(1R,2R)-2-(5,5-dimethyl-1-hexynyl)cyclopropyl]-
• 1H-Imidazole, 5-[(1R,2R)-2-(5,5-dimethyl-1-hexyn-1-yl)cyclopropyl]-
• 1H-imidazole, 4-[2-(5,5-dimethyl-1-hexyn-1-yl)cyclopropyl]-
• 4-(2-(5,5-Dimethylhex-1-Ynyl)Cyclopropyl)Imidazole
• 4-[2-(5,5-dimethylhex-1-yn-1-yl)cyclopropyl]-1H-imidazole
• 5-[(1R,2R)-2-(5,5-Dimethyl-1-hexyn-1-yl)cyclopropyl]-1H-imidazole
• Cipralisant

4-(2-(5,5-Dimethylhex-1-inyl)-cyclopropyl)imidazol

CAS: 213027-19-1

4-(2-(5,5-Dimethylhex-1-inyl)-cyclopropyl)imidazol is an analog of glutamine and a potent inhibitor of the enzyme glutaminase. It is used as a research tool to study energy metabolism and its role in inflammatory bowel disease. 4-(2-(5,5-Dimethylhex-1-inyl)-cyclopropyl)imidazol has been shown to reduce locomotor activity in mice by inhibiting the production of glutaminyl cyclase, which synthesizes this neurotransmitter. This compound also inhibits the release of inflammatory mediators from mast cells and macrophages, thereby reducing inflammation. 4-(2-(5,5-Dimethylhex-1-inyl)-cyclopropyl)imidazol has been shown to be effective against symptoms associated with nervous system diseases such as Parkinson's disease.

Formula: C₁₄H₂₀N₂

Purity: Min. 95%

Molecular weight: 216.32 g/mol

Ref: 3D-NIA02719

Cipralisant

CAS: 213027-19-1

Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.

Formula: C₁₄H₂₀N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 216.32

Ref: TM-T14970