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CAS 21312-10-7

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Acetylsulfamethoxazole

Description:
Acetylsulfamethoxazole is a sulfonamide antibiotic that is primarily used in combination with trimethoprim to treat various bacterial infections. It is characterized by its sulfonamide functional group, which is essential for its antibacterial activity. The compound exhibits good solubility in water, which facilitates its absorption and distribution in the body. Acetylsulfamethoxazole works by inhibiting bacterial folic acid synthesis, thereby preventing the growth and reproduction of bacteria. Its chemical structure includes an acetyl group, which enhances its pharmacological properties compared to its parent compound, sulfamethoxazole. The substance is typically administered orally and is known for its effectiveness against a range of gram-positive and gram-negative bacteria. However, like other sulfonamides, it may cause allergic reactions in some individuals and can lead to side effects such as gastrointestinal disturbances or skin rashes. Proper dosage and monitoring are essential to minimize potential adverse effects and ensure therapeutic efficacy.
Formula:C12H13N3O4S
InChI:InChI=1S/C12H13N3O4S/c1-8-7-12(14-19-8)15-20(17,18)11-5-3-10(4-6-11)13-9(2)16/h3-7H,1-2H3,(H,13,16)(H,14,15)
InChI key:InChIKey=GXPIUNZCALHVBA-UHFFFAOYSA-N
SMILES:N(S(=O)(=O)C1=CC=C(NC(C)=O)C=C1)C2=NOC(C)=C2
Synonyms:
  • 4′-Acetyl-3-sulfa-5-methylisoxazole
  • Acetamide, N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]-
  • Acetanilide, 4′-[(5-methyl-3-isoxazolyl)sulfamoyl]-
  • Acetylsulfamethoxazole
  • N-Acetylsulfamethoxazole
  • N-[4-[[(5-Methyl-3-isoxazolyl)amino]sulfonyl]phenyl]acetamide
  • N-{4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl}acetamide
  • N4-Acetylsulfamethoxazole
  • N<sub>4</sub>-Acetylsulfamethoxazole
  • N<sup>4</sup>-Acetylsulfamethoxazole
  • See more synonyms
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