CAS 21312-10-7: Acetylsulfamethoxazole

Description: Acetylsulfamethoxazole is a sulfonamide antibiotic that is primarily used in combination with trimethoprim to treat various bacterial infections. It is characterized by its sulfonamide functional group, which is essential for its antibacterial activity. The compound exhibits good solubility in water, which facilitates its absorption and distribution in the body. Acetylsulfamethoxazole works by inhibiting bacterial folic acid synthesis, thereby preventing the growth and reproduction of bacteria. Its chemical structure includes an acetyl group, which enhances its pharmacological properties compared to its parent compound, sulfamethoxazole. The substance is typically administered orally and is known for its effectiveness against a range of gram-positive and gram-negative bacteria. However, like other sulfonamides, it may cause allergic reactions in some individuals and can lead to side effects such as gastrointestinal disturbances or skin rashes. Proper dosage and monitoring are essential to minimize potential adverse effects and ensure therapeutic efficacy.

Formula: C₁₂H₁₃N₃O₄S

InChI: InChI=1S/C12H13N3O4S/c1-8-7-12(14-19-8)15-20(17,18)11-5-3-10(4-6-11)13-9(2)16/h3-7H,1-2H3,(H,13,16)(H,14,15)

InChI key: InChIKey=GXPIUNZCALHVBA-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(C=C1)S(=O)(=O)NC2=NOC(=C2)C)C

Synonyms:

• 4′-Acetyl-3-sulfa-5-methylisoxazole
• Acetamide, N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]-
• Acetanilide, 4′-[(5-methyl-3-isoxazolyl)sulfamoyl]-
• Acetylsulfamethoxazole
• N-Acetylsulfamethoxazole
• N-[4-[[(5-Methyl-3-isoxazolyl)amino]sulfonyl]phenyl]acetamide
• N-{4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl}acetamide
• N4-Acetylsulfamethoxazole
• N₄-Acetylsulfamethoxazole
• N⁴-Acetylsulfamethoxazole
• N⁴-Acetylsulfisomezole
• Stx 606
• Sulfisomezole-N⁴-acetate
• Sulfisomezole-N4-acetate
• N4-Acetylsulfisomezole

Sulfamethoxazole impurity A CRS

CAS: 21312-10-7

• Formula: C₁₂H₁₃N₃O₄S
• Molecular weight: 295.3143

Sulfamethoxazole Related Compound A (N-{4-[N-(5-methylisoxazol-3-yl)sulfamoyl]phenyl}acetamide)

CAS: 21312-10-7

Sulfonamides, nesoi

• Formula: C₁₂H₁₃N₃O₄S
• Color and Shape: White Crystalline Powder
• Molecular weight: 295.06268

N-(4-(N-(5-Methylisoxazol-3-yl)sulfamoyl)phenyl)acetamide

CAS: 21312-10-7

• Formula: C₁₂H₁₃N₃O₄S
• Purity: %
• Color and Shape: Solid
• Molecular weight: 295.3143

Sulfamethoxazole EP Impurity A (Sulfamethoxazole USP Related Compound A)

CAS: 21312-10-7

• Formula: C₁₂H₁₃N₃O₄S
• Color and Shape: White To Off-White Solid
• Molecular weight: 295.31

N-[4-[(5-Methylisoxazol-3-yl)sulphamoyl]phenyl]acetamide

CAS: 21312-10-7

• Formula: C₁₂H₁₃N₃O₄S
• Color and Shape: Neat
• Molecular weight: 295.31

Acetylsulfamethoxazole

CAS: 21312-10-7

• Formula: C₁₂H₁₃N₃O₄S
• Color and Shape: Neat
• Molecular weight: 295.31

N4-Acetylsulfamethoxazole

CAS: 21312-10-7

N-acetyl Sulfamethoxazole is a metabolite of sulfamethoxazole, an antibiotic with antiviral activity, that can be …

• Formula: C₁₂H₁₃N₃O₄S
• Purity: 98.81%
• Color and Shape: Solid
• Molecular weight: 295.31

N4-Acetylsulfamethoxazole

CAS: 21312-10-7

• Formula: C₁₂H₁₃N₃O₄S
• Purity: ≥ 99.0%
• Color and Shape: White to off-white solid
• Molecular weight: 295.31

N-(4-(N-(5-Methylisoxazol-3-yl)sulfamoyl)phenyl)acetamide

CAS: 21312-10-7

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 295.30999755859375

N-Acetyl Sulfamethoxazole

CAS: 21312-10-7

Impurity Sulfamethoxazole EP Impurity A Applications A metabolite of Sulfamethoxazole. References Ciolino, H., et al.: …

• Formula: C₁₂H₁₃N₃O₄S
• Color and Shape: Off-White
• Molecular weight: 295.31

N-Acetyl Sulfamethoxazole-13C6

CAS: 21312-10-7

• Formula: C₆₁₃C₆H₁₃N₃O₄S
• Color and Shape: Neat
• Molecular weight: 301.27

N-Acetyl sulfamethoxazole

CAS: 21312-10-7

N-Acetyl sulfamethoxazole is a sulfa drug that inhibits bacterial growth by inhibiting the production of …

• Formula: C₁₂H₁₃N₃O₄S
• Purity: Min. 95%
• Molecular weight: 295.32 g/mol