CAS 213211-10-0

5(R)-(4-Bromobenzyl)-3-(3,5-dichlorophenyl)-1,5-dimethylimidazolidine-2,4-dione

Description:

5(R)-(4-Bromobenzyl)-3-(3,5-dichlorophenyl)-1,5-dimethylimidazolidine-2,4-dione, with the CAS number 213211-10-0, is a synthetic organic compound characterized by its imidazolidine core structure, which features two carbonyl groups (diones) and various substituents that contribute to its chemical properties. The presence of a bromobenzyl group and dichlorophenyl group indicates significant hydrophobic characteristics, which may influence its solubility and reactivity. This compound is likely to exhibit biological activity due to its structural motifs, making it of interest in medicinal chemistry. Its stereochemistry, indicated by the (R) configuration, suggests specific spatial arrangements that can affect its interaction with biological targets. The compound's stability, reactivity, and potential applications in pharmaceuticals or agrochemicals would depend on its functional groups and overall molecular geometry. As with many synthetic compounds, safety and handling precautions should be observed, given the presence of halogenated groups, which can pose environmental and health risks.

Formula: C₁₈H₁₅BrCl₂N₂O₂

Synonyms:

• Birt-0377
• Birt-377

BIRT-377

CAS: 213211-10-0

BIRT-377

Purity: ≥98%

Molecular weight: 442.13g/mol

Ref: 54-BUP03236

BIRT 377

Controlled Product

CAS: 213211-10-0

Formula: C₁₈H₁₅BrCl₂N₂O₂

Color and Shape: Neat

Molecular weight: 442.13

Ref: TR-B399710

BIRT 377

CAS: 213211-10-0

BIRT 377 is a humanized monoclonal antibody with specificity for the inflammatory molecule MCP-1. It is being developed as a therapy for inflammatory bowel disease, which is characterized by chronic inflammation of the gastrointestinal tract. BIRT 377 binds to MCP-1 and blocks its interaction with the receptor CCR2 on the surface of cells in the gastrointestinal tract. This prevents inflammatory responses that are responsible for tissue damage and ulceration. BIRT 377 has been shown to be effective in animal models of inflammatory bowel disease, and clinical studies are underway in humans.

Formula: C₁₈H₁₅BrCl₂N₂O₂

Purity: Min. 95%

Molecular weight: 442.1 g/mol

Ref: 3D-NIA21110

BIRT-377

CAS: 213211-10-0

BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).

Formula: C₁₈H₁₅BrCl₂N₂O₂

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 442.13

Ref: TM-T23796