CAS 2133-40-6

L-Proline, methyl ester, hydrochloride (1:1)

Description:

L-Proline, methyl ester, hydrochloride (1:1) is a chemical compound that serves as a derivative of the amino acid proline. It is characterized by the presence of a methyl ester group, which enhances its solubility in organic solvents and may influence its biological activity. The hydrochloride form indicates that the compound is a salt, which typically improves stability and solubility in aqueous solutions. This compound is often utilized in peptide synthesis and as an intermediate in organic synthesis due to its ability to participate in various chemical reactions. L-Proline itself is a non-essential amino acid that plays a crucial role in protein synthesis and is involved in various metabolic processes. The methyl ester modification can affect the compound's reactivity and interaction with biological systems. As with many chemical substances, handling should be done with care, adhering to safety protocols to avoid exposure. Overall, L-Proline, methyl ester, hydrochloride is a valuable compound in both research and industrial applications.

Formula: C₆H₁₁NO₂·ClH

InChI: InChI=1S/C6H11NO2.ClH/c1-9-6(8)5-3-2-4-7-5;/h5,7H,2-4H2,1H3;1H/t5-;/m0./s1

InChI key: InChIKey=HQEIPVHJHZTMDP-JEDNCBNOSA-N

SMILES: C(OC)(=O)[C@@H]1CCCN1.Cl

Synonyms:

• (2S)-(Methoxycarbonyl)pyrrolidine hydrochloride
• (2S)-2-(methoxycarbonyl)pyrrolidinium
• (S)-Methyl pyrrolidine-2-carboxylate hydrochloride
• (S)-Proline methyl ester hydrochloride
• (S)-Pyrrolidine-2-carboxylic acid methyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Pro-OMe hydrochloride
• <span class="text-smallcaps">L</span>-Proline methyl ester monohydrochloride
• <span class="text-smallcaps">L</span>-Proline, methyl ester, hydrochloride
• <span class="text-smallcaps">L</span>-Proline, methyl ester, hydrochloride (1:1)
• H-Pro-OMe.HCl
• H-Pro-OMe・HCl
• Methyl <span class="text-smallcaps">L</span>-prolinate hydrochloride
• Methyl Prolinate
• Methyl Prolinate Hydrochloride (1:1)
• Methyl prolinate hydrochloride
• Methyl proline hydrochloride
• Proline, methyl ester, hydrochloride, <span class="text-smallcaps">L</span>-
• methyl L-prolinate
• methyl L-prolinate hydrochloride
• L-Proline, methyl ester, hydrochloride
• Proline, methyl ester, hydrochloride, L-

L-Proline Methyl Ester Hydrochloride

CAS: 2133-40-6

Formula: C₆H₁₁NO₂·HCl

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 165.62

Ref: 3B-P0342

L-Proline methyl ester hydrochloride, 98+%

CAS: 2133-40-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₁₂NO₂

Purity: 98+%

Color and Shape: White, Crystals or powder or crystalline powder or lumps

Molecular weight: 130.17

Ref: 02-L19290

H-Pro-OMe · HCl

CAS: 2133-40-6

Bachem ID: 4000661.

Formula: C₆H₁₁NO₂·HCl

Purity: > 99%

Color and Shape: White

Molecular weight: 165.62

Ref: 01-4000661

L-Proline methyl ester, HCl

CAS: 2133-40-6

Formula: C₆H₁₂ClNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 165.6180

Ref: IN-DA0038W7

Methyl (2S)-pyrrolidine-2-carboxylate hydrochloride

CAS: 2133-40-6

Methyl (2S)-pyrrolidine-2-carboxylate hydrochloride

Formula: C₆H₁₁NO₂·ClH

Purity: 98%

Color and Shape: white solid

Molecular weight: 165.62g/mol

Ref: 54-OR11387

L-Proline methyl ester hydrochloride

CAS: 2133-40-6

Formula: C₆H₁₁NO₂HCl

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 165.62

Ref: 7W-GM3370

L-Proline Methyl Ester Hydrochloride

CAS: 2133-40-6

Stability Hygroscopic
Applications L-Proline Methyl Ester Hydrochloride (cas# 2133-40-6) is a compound useful in organic synthesis.

Formula: C₆H₁₁NO₂·ClH

Color and Shape: White To Off-White

Molecular weight: 165.618

Ref: TR-P755980

L-Proline methyl ester hydrochloride

CAS: 2133-40-6

L-Proline methyl ester hydrochloride is an organic compound that is classified as a trifluoroacetic acid ester. It has significant antiproliferative activity and induces apoptotic cell death in colorectal carcinoma cells. L-Proline methyl ester hydrochloride also inhibits the proliferation of lymphocytes by inhibiting protein synthesis, which may be due to its conformational properties. L-Proline methyl ester hydrochloride is synthesized by reacting L-proline with trifluoroacetic acid and subsequently hydrolyzing the resulting ester with hydrochloric acid. The synthesis can be carried out in two steps: first, a chloride ion is added to the protonated form of the amine; second, the protonated form of the amine reacts with hydrophobic compounds such as dodecyl amines or ethyl acetate to form an alkyl group. This reaction can also be carried out using

Formula: C₆H₁₂ClNO₂

Color and Shape: White Powder

Molecular weight: 165.62 g/mol

Ref: 3D-FP27178

H-Pro-OMe.HCl

CAS: 2133-40-6

M02956 - H-Pro-OMe.HCl

Formula: C₆H₁₂ClNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 165.62

Ref: 10-M02956

L-Proline-2,5,5-d3 Methyl Ester Hydrochloride

Controlled Product

CAS: 2133-40-6

Applications L-Proline-2,5,5-d3 Methyl Ester Hydrochloride is an intermediate in the synthesis of L-Prolinamide-2,5,5-d3 (P755976), a proline based organocatalyst.
References Alberg, D., et al.: Bioorg. Med. Chem. Lett., 19, 3888 (2009), Huang, X., et al.: J. Phys. Chem., 114, 1068 (2010),

Formula: C₆H₈D₃NO₂•HCl

Color and Shape: Neat

Molecular weight: 168.64

Ref: TR-P755982

L-Proline Methyl Ester Hydrochloride

CAS: 2133-40-6

Formula: C₆H₁₁NO₂HCl

Molecular weight: 129.16:36.46

Ref: ST-EA-CP-E12039