CAS 21331-43-1

2-Amino-4-(2-naphthyl)thiazole

Description:

2-Amino-4-(2-naphthyl)thiazole is an organic compound characterized by its thiazole ring, which is a five-membered heterocyclic structure containing both sulfur and nitrogen atoms. This compound features an amino group (-NH2) and a naphthyl group, which is derived from naphthalene, attached to the thiazole ring. The presence of the amino group contributes to its potential as a building block in pharmaceuticals and agrochemicals, as it can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. The thiazole moiety is known for its biological activity, often exhibiting antimicrobial and antifungal properties. Additionally, the naphthyl group enhances the compound's hydrophobic characteristics, influencing its solubility and interaction with biological membranes. Overall, 2-Amino-4-(2-naphthyl)thiazole is of interest in medicinal chemistry and materials science due to its unique structural features and potential applications.

Formula: C₁₃H₁₀N₂S

InChI: InChI=1/C13H10N2S/c14-13-15-12(8-16-13)11-6-5-9-3-1-2-4-10(9)7-11/h1-8H,(H2,14,15)

InChI key: InChIKey=GWDNDNTTXIIXRS-UHFFFAOYSA-N

SMILES: NC1=NC(C2=CC3=C(C=C2)C=CC=C3)=CS1

Synonyms:

• 2-Amino-4-(naphthalen-2-yl)thiazole
• 2-Amino-4-β-naphthylthiazole
• 2-Thiazolamine, 4-(2-naphthalenyl)-
• 4-(2-Naphthalenyl)-2-thiazolamine
• 4-(2-Naphthyl)-2-amino-1,3-thiazole
• 4-(2-Naphthyl)-2-thiazolamine
• 4-(Naphthalen-2-Yl)-1,3-Thiazol-2-Amine
• Thiazole, 2-amino-4-(2-naphthyl)-
• 2-Amino-4-(2-naphthyl)thiazole
• 4-NAPHTHALEN-2-YL-THIAZOL-2-YLAMINE
• IFLAB-BB F1386-0377
• AKOS BBS-00000618
• 4-(2-NAPHTHYL)-1,3-THIAZOL-2-YLAMINE
• 4-(NAPHTHALEN-2-YL)THIAZOL-2-AMINE
• 4-(2-NAPHTHYL)-1,3-THIAZOL-2-AMINE

2-Amino-4-(2-naphthyl)thiazole, 98%

CAS: 21331-43-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₃H₁₀N₂S

Purity: 98%

Color and Shape: Powder, Pale cream

Molecular weight: 226.30

Ref: 02-B23223

4-(2-Naphthyl)-1,3-thiazol-2-amine hydrobromide

CAS: 21331-43-1

Formula: C₁₃H₁₀N₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 226.2969

Ref: IN-DA003GE1

2-Amino-4-(2-Naphthyl)Thiazole

CAS: 21331-43-1

2-Amino-4-(2-Naphthyl)Thiazole

Purity: 98%

Molecular weight: 226.30g/mol

Ref: 54-OR1010262

4-Naphthalen-2-yl-thiazol-2-ylamine

CAS: 21331-43-1

Purity: 95.0%

Color and Shape: Solid, No data available.

Molecular weight: 226.3000030517578

Ref: 10-F014138

4-Naphthalen-2-yl-thiazol-2-yl-amine

CAS: 21331-43-1

4-Naphthalen-2-yl-thiazol-2-yl-amine is a naphthalene derivative which has been shown to be active against gram-negative bacteria. It inhibits bacterial growth by binding to the ribosomes and preventing protein synthesis. The antibiotic binds to the dihedral site of the 30S ribosomal subunit and stabilizes the binding of ciprofloxacin, an antibiotic that inhibits bacterial DNA synthesis. 4NTZ2A has also been shown to have antifungal activity, inhibiting cell growth in Candida albicans, Saccharomyces cerevisiae and Cryptococcus neoformans. This drug also has antibacterial activity against gram-negative bacteria such as Escherichia coli, Proteus vulgaris and Salmonella typhimurium. The antibacterial activity is due to its ability to inhibit aldehyde dehydrogenase, which converts fatty acids into aldehydes that

Formula: C₁₃H₁₀N₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 226.3 g/mol

Ref: 3D-FN54155