CAS 21339-55-9: 1-Methyl-L-tryptophan

Description: 1-Methyl-L-tryptophan is an amino acid derivative and a structural analog of the essential amino acid L-tryptophan. It is characterized by the presence of a methyl group attached to the nitrogen atom of the indole side chain, which alters its biochemical properties. This compound is often studied for its role in modulating immune responses and its potential effects on serotonin metabolism. It has been investigated for its ability to inhibit the enzyme indoleamine 2,3-dioxygenase (IDO), which is involved in the catabolism of tryptophan and plays a significant role in immune regulation and tumor biology. 1-Methyl-L-tryptophan is typically found in a crystalline form and is soluble in polar solvents. Its applications extend to research in immunology, cancer therapy, and neurobiology, where it may influence pathways related to inflammation and neurotransmitter synthesis. As with many biochemical compounds, its safety and efficacy in various applications depend on concentration and context of use.

Formula: C₁₂H₁₄N₂O₂

InChI: InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m0/s1

InChI key: InChIKey=ZADWXFSZEAPBJS-JTQLQIEISA-N

SMILES: O=C(O)C(N)CC1=CN(C=2C=CC=CC21)C

Synonyms:

• (S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
• 1-Methyl-<span class="text-smallcaps">L</span>-tryptophan
• 1-Methyltryptophan
• <span class="text-smallcaps">L</span>-(-)-1-Methyltryptophan
• <span class="text-smallcaps">L</span>-Tryptophan, 1-methyl-
• DL-1-Methyltryptophan
• L-(-)-1-Methyltryptophan
• L-Tryptophan, 1-methyl-
• NSC 77678
• Tryptophan, 1-methyl-, <span class="text-smallcaps">L</span>-
• Tryptophan, 1-methyl-, L-
• 1-Methyl-L-tryptophan

H-Trp(1-Me)-OH

CAS: 21339-55-9

• Formula: C₁₂H₁₄N₂O₂
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 218.2518

1-Methyl-L-tryptophan

CAS: 21339-55-9

• Molecular weight: 218.25

1-Methyl-L-tryptophan

CAS: 21339-55-9

• Formula: C₁₂H₁₄N₂O₂
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 218.26

(S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid

CAS: 21339-55-9

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 218.25599670410156

1-Methyl-L-tryptophan

CAS: 21339-55-9

• Formula: C₁₂H₁₄N₂O₂
• Purity: 98%
• Molecular weight: 218.256

(S)-Indoximod

CAS: 21339-55-9

(S)-Indoximod (L-Abrine) is an indoleamine-2,3-dioxygenase (IDO) inhibitor for cancer research.

• Formula: C₁₂H₁₄N₂O₂
• Purity: 95.39%
• Color and Shape: Solid
• Molecular weight: 218.25

(S)-2-Amino-3-(1-methyl-1h-indol-3-yl)propanoic Acid

CAS: 21339-55-9

Applications (S)-2-Amino-3-(1-methyl-1h-indol-3-yl)propanoic acid

• Formula: C₁₂H₁₄N₂O₂
• Color and Shape: Neat
• Molecular weight: 218.25

1-Methyl-L-tryptophan

CAS: 21339-55-9

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• Formula: C₁₂H₁₄N₂O₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 218.25 g/mol