CAS 21343-40-8

25-Hydroxyvitamin D

Description:

25-Hydroxyvitamin D, also known as calcifediol, is a secosteroid and an active metabolite of vitamin D. It plays a crucial role in calcium and phosphate metabolism, which is essential for maintaining bone health and overall physiological functions. This compound is produced in the liver from vitamin D3 (cholecalciferol) or vitamin D2 (ergocalciferol) after they are synthesized in the skin or ingested through diet. 25-Hydroxyvitamin D is typically measured in the blood to assess an individual's vitamin D status, as it reflects the total vitamin D obtained from both sunlight and dietary sources. The substance is characterized by its fat-soluble nature, allowing it to be stored in body tissues. Its biological activity is primarily mediated through the vitamin D receptor, influencing gene expression related to calcium absorption and bone mineralization. Deficiency in 25-hydroxyvitamin D can lead to various health issues, including rickets in children and osteomalacia in adults. Its CAS number is 21343-40-8, which uniquely identifies this compound in chemical databases.

Formula: C₂₈H₄₄O₂

InChI: InChI=1/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12+,23-13-/t20-,21+,24+,25?,26+,28-/m1/s1

InChI key: InChIKey=KJKIIUAXZGLUND-ICCVIKJNSA-N

SMILES: C[C@@]12[C@](\C(=C\C=C\3/C(=C)CC[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](/C=C/[C@@H](C(C)(C)O)C)C)[H])[H]

Synonyms:

• (1S,3Z)-4-Methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexenyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]cyclohexanol
• (3S,5Z,7E,17ξ,22E)-9,10-secoergosta-5,7,10,22-tetraene-3,25-diol
• (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-3,25-diol
• 25-Hydroxycalciferol
• 25-Hydroxyergocalciferol
• 25-Hydroxyvitamin D
• 25-Hydroxyvitamin D₂
• 25-hydroxy VD2
• 9,10-Secoergosta-5,7,10(19),22-tetraene-3,25-diol, (3β,5Z,7E,22E)-
• 9,10-Secoergosta-5,7,10(19),22-tetraene-3β,25-diol
• Cyclohexanol, 4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexenyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1S,3Z)-
• Ercalcidiol
• (E,3S,6S)-6-[(1R,3aR,4E,7aS)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylidene-cyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2,3-dimethyl-hept-4-en-2-ol
• 3-{2-[1-(5-Hydroxy-1,4,5-trimethyl-hex-2-enyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexanol ( 25-Hydroxyvitamin D2 )
• 25-Hydroxycalciferol, 25-Hydroxyergocalciferol
• 25-hydroxyvitamind
• 25-hydoxyergocalciferol
• (5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetrene-3β,25-diol

25-Hydroxyvitamin D2

CAS: 21343-40-8

Formula: C₂₈H₄₄O₂

Purity: ≥ 95.0%

Color and Shape: White powder

Molecular weight: 412.65

Ref: 7W-GV3532

Ercalcidiol

CAS: 21343-40-8

Ercalcidiol

Purity: ≥98%

Molecular weight: 412.65g/mol

Ref: 54-BUP01262

Ercalcidiol

CAS: 21343-40-8

Ercalcidiol is a metabolite of vitamin D2 and can be used in monitoring vitamin D therapy.

Formula: C₂₈H₄₄O₂

Purity: 99.62%

Color and Shape: Solid

Molecular weight: 412.65

Ref: TM-T15242

25-Hydroxy-Ergocalciferol (25-(OH)-Vitamin D2)

CAS: 21343-40-8

Formula: C₂₈H₄₄O₂

Color and Shape: White To Off-White Solid

Molecular weight: 412.66

Ref: 4Z-V-038003

25-Hydroxy Vitamin D2

Controlled Product

CAS: 21343-40-8

Stability Light Sensitive, Temperature Sensitive
Applications A metabolite of Vitamin D2 (V676040).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Barnes, P., et al.: J. Clin. Invest., 83, 1527 (1989), Holick, M., et al.: J. Cell Biochem., 88(2), 296 (2003), Maunsell, Z., et al.: Clin. Chem., 51, 1683 (2005),

Formula: C₂₈H₄₄O₂

Color and Shape: White To Light Yellow

Molecular weight: 412.65

Ref: TR-H995820

25-Hydroxy vitamin D2

CAS: 21343-40-8

25-Hydroxy vitamin D2 is a reagent that belongs to the category of complex compounds. It is a fine chemical and useful scaffold with a CAS number of 21343-40-8. This compound can be used as an intermediate, useful building block, or reaction component. 25-Hydroxy vitamin D2 has been shown to be a versatile building block in organic synthesis. It is also used as an intermediate in the synthesis of 25-hydroxyvitamin D3, which is a hormone involved in calcium and phosphate homeostasis.

Formula: C₂₈H₄₄O₂

Purity: Min. 95%

Molecular weight: 412.65 g/mol

Ref: 3D-XH182782

25-Hydroxyvitamin D2

CAS: 21343-40-8

Formula: C₂₈H₄₄O₂

Molecular weight: 412.66

Ref: ST-EA-CP-E70019