CAS 213550-82-4

Pyridine, 3-[(2S)-2-azetidinylmethoxy]-5-iodo-

Description:

Pyridine, 3-[(2S)-2-azetidinylmethoxy]-5-iodo- is a chemical compound characterized by its pyridine ring, which is a six-membered aromatic heterocycle containing one nitrogen atom. The presence of the azetidine moiety, a four-membered saturated ring, contributes to its unique structural properties and potential biological activity. The compound features a methoxy group attached to the azetidine, which can influence its solubility and reactivity. The iodine substituent at the 5-position of the pyridine ring may enhance its reactivity in various chemical reactions, including nucleophilic substitutions and coupling reactions. This compound may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry. Its specific stereochemistry, indicated by the (2S) designation, suggests that it may have distinct interactions with biological targets. Overall, the combination of these functional groups and structural features makes this compound a candidate for further research in drug development and synthetic chemistry.

Formula: C₉H₁₁IN₂O

5-Iodo-A-85380 dihydrochloride hydrate

CAS: 213550-82-4

Formula: C₉H₁₁IN₂O·2HCl·xH₂O

Molecular weight: 363.02 (anhydrous)

Ref: 7W-GK5152

3-((2S)-2-Azetidinylmethoxy)-5-iodo-pyridine

CAS: 213550-82-4

3-((2S)-2-Azetidinylmethoxy)-5-iodo-pyridine is a neuroprotective agent that binds to the α7 nicotinic acetylcholine receptor. It has been shown to be active in animal models of stroke, Parkinson's disease, and Alzheimer's disease. The effects of 3-((2S)-2-Azetidinylmethoxy)-5-iodo-pyridine on glutamate toxicity were studied in Sprague Dawley rats. This compound was found to be protective against glutamate toxicity when administered before the glutamate insult. Functional assays revealed that 3-(2S)-2-azetidinylmethoxy) 5-iodo pyridine is a potent agonist for the α7 nicotinic acetylcholine receptor subunit.

Formula: C₉H₁₁IN₂O

Purity: Min. 95%

Molecular weight: 290.1 g/mol

Ref: 3D-NIA55082