CAS 2135514-20-2

4(1H)-Pyrimidinone, 1-(2,6-dimethoxyphenyl)-2-(ethoxymethyl)-6-hydroxy-5-[[(3R)-3-phenyl-1-pyrrolidinyl]carbonyl]-

Description:

4(1H)-Pyrimidinone, 1-(2,6-dimethoxyphenyl)-2-(ethoxymethyl)-6-hydroxy-5-[[(3R)-3-phenyl-1-pyrrolidinyl]carbonyl]- is a complex organic compound characterized by its pyrimidinone core structure, which features a six-membered aromatic ring containing nitrogen atoms. This compound includes various functional groups, such as methoxy groups, an ethoxymethyl side chain, and a phenyl-pyrrolidine moiety, contributing to its potential biological activity. The presence of hydroxyl and carbonyl groups suggests it may engage in hydrogen bonding, influencing its solubility and reactivity. The stereochemistry indicated by the (3R) configuration of the pyrrolidine ring may affect its interaction with biological targets, making it of interest in medicinal chemistry. This compound's unique structure may confer specific pharmacological properties, potentially making it a candidate for further research in drug development. However, detailed studies would be necessary to elucidate its full chemical behavior and therapeutic potential.

Formula: C₂₆H₂₉N₃O₆

Synonyms:

• APJ receptor agonist 5
• 4(1H)-Pyrimidinone, 1-(2,6-dimethoxyphenyl)-2-(ethoxymethyl)-6-hydroxy-5-[[(3R)-3-phenyl-1-pyrrolidinyl]carbonyl]-

APJ receptor agonist 5

CAS: 2135514-20-2

Potent oral APJ agonist (EC 50:0.4 nM); improves cardiac function in HF, with good pharmacokinetics and safety.

Formula: C₂₆H₂₉N₃O₆

Color and Shape: Solid

Molecular weight: 479.52

Ref: TM-T63153