CAS 2136270-20-5

SPOP-IN-6b

Description:

SPOP-IN-6b is a small molecule inhibitor that targets the SPOP (speckle-type POZ protein) protein, which plays a significant role in various cellular processes, including protein degradation and signaling pathways. This compound is part of a class of inhibitors designed to disrupt the interaction between SPOP and its substrates, potentially influencing cancer cell proliferation and survival. The chemical structure of SPOP-IN-6b typically features specific functional groups that enhance its binding affinity and selectivity for the SPOP protein. Its mechanism of action involves modulating the ubiquitin-proteasome system, which is crucial for maintaining cellular homeostasis. Research into SPOP-IN-6b may provide insights into therapeutic strategies for cancers associated with SPOP mutations or dysregulation. As with many small molecule inhibitors, the pharmacokinetics, bioavailability, and toxicity profiles are essential considerations for its development and potential clinical applications. Further studies are necessary to fully elucidate its efficacy and safety in biological systems.

Formula: C₂₈H₃₂N₆O₃

Synonyms:

• 2H-Dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide, 1,5-dihydro-2-imino-10-methyl-N-[3-(4-morpholinyl)propyl]-5-oxo-1-(2-phenylethyl)-
• SPOP-IN-6b

SPOP-IN-6b

CAS: 2136270-20-5

SPOP-IN-6b

Purity: ≥98%

Molecular weight: 500.59g/mol

Ref: 54-BUP11574

SPOP-IN-6b

CAS: 2136270-20-5

SPOP-IN-6b is a research tool used to study protein interactions. SPOP-IN-6b can be used as an inhibitor of Kv1.3, a voltage-gated potassium channel that is important for the regulation of neuronal excitability and seizure activity. SPOP-IN-6b binds to the ligand binding site on Kv1.3, preventing activation by potassium ions. This inhibits neuronal excitability and the development of seizures in animal models.

Formula: C₂₈H₃₂N₆O₃

Purity: Min. 95%

Molecular weight: 500.6 g/mol

Ref: 3D-LKD27020

SPOP-IN-6b

CAS: 2136270-20-5

SPOP-IN-6b is an effective inhibitor of speckle-type POZ protein (SPOP) with an IC50 of 3.58 μM and can be used in stuides about the treatment of renal cancer.

Formula: C₂₈H₃₂N₆O₃

Purity: 99.83%

Color and Shape: Solid

Molecular weight: 500.59

Ref: TM-T16922