CAS 2137-18-0

Gestonorone

Description:

Gestonorone, with the CAS number 2137-18-0, is a synthetic steroid that belongs to the class of progestins, which are compounds that mimic the action of the natural hormone progesterone. It is primarily used in hormonal therapies and contraceptive formulations. Gestonorone exhibits characteristics typical of progestins, including the ability to regulate menstrual cycles, support pregnancy, and influence various physiological processes related to reproduction. The compound is known for its anti-estrogenic properties and is often utilized in combination with estrogen in contraceptive pills to enhance efficacy and reduce side effects. Its mechanism of action involves binding to progesterone receptors, leading to changes in gene expression that affect the endometrium and other reproductive tissues. Additionally, Gestonorone may have effects on metabolic processes and can influence lipid profiles. As with other synthetic hormones, its use may be associated with side effects, and its safety profile is evaluated in clinical settings. Overall, Gestonorone plays a significant role in reproductive health and hormonal regulation.

Formula: C₂₀H₂₈O₃

InChI: InChI=1/C20H28O3/c1-12(21)20(23)10-8-18-17-5-3-13-11-14(22)4-6-15(13)16(17)7-9-19(18,20)2/h11,15-18,23H,3-10H2,1-2H3

InChI key: InChIKey=GTFUITFQDGVJSK-XGXHKTLJSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@@]4(C(CC3)=CC(=O)CC4)[H])(CC1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]

Synonyms:

• 17-Acetyl-17-Hydroxyestr-4-En-3-One
• 17-Alpha-Hydroxy-19-Norpregn-4-Ene-3,20-Dione
• 17-Hydroxy-19-Norpregn-4-Ene-3,20-Dione
• 17A-Hydroxy-19-Norprogesterone
• 17Alpha-Hydroxy-19-Norpregn-4-En-3,20-Dione
• 17α-17-Acetyl-17-hydroxyestr-4-en-3-one
• 17α-Hydroxy-19-norpregn-4-en-3,20-dione
• 17α-Hydroxy-19-norpregn-4-ene-3,20-dione
• 17β-Acetyl-17α-hydroxyestr-4-en-3-one
• 19-Nor-4-Pregnen-17-Ol-3,20-Dione
• 19-Nor-4-pregene-17-ol-3,20-dione
• 19-Norpregn-4-en-3,20-dione-17α-ol
• 19-Norpregn-4-ene-3,20-dione, 17-hydroxy-
• Gestonorone Base:17Alpha-Hydroxy-19-Norpregn-4-En-3,20-Dione
• Gestronol
• Tx 045
• Gestonorone

Gestonorone

CAS: 2137-18-0

Gestonorone is steroid progesterone in the 19-nometroprogesterone and 17α -hydroxyprogesterone groups.

Formula: C₂₀H₂₈O₃

Color and Shape: White Or Almost White Crystalline Powder

Molecular weight: 316.43

Ref: TM-T31924

Gestonorone

CAS: 2137-18-0

Formula: C₂₀H₂₈O₃

Molecular weight: 316.43

Ref: 7W-GP4049

Gestonorone

Controlled Product

CAS: 2137-18-0

Gestonorone is an anti-infective drug that has been used to treat infectious diseases. It blocks the uptake of nomegestrol acetate by liver cells, which can be used for cancer treatment. It can also be used for autoimmune diseases and as a contraceptive agent. Gestonorone prevents the uptake of nomegestrol acetate by liver cells and blocks glucocorticoid receptors in vitro. Gestonorone has been shown to inhibit the growth of certain cancer cells in vivo, but not others. This drug can also be used as a contraceptive agent or for autoimmune diseases.

Formula: C₂₀H₂₈O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 316.43 g/mol

Ref: 3D-FG39643

Gestonorone

Controlled Product

CAS: 2137-18-0

Applications Gestonorone is a steroidal progestin. It has been shown to have accelerated body weight gain and caused the atrophy of the prostate, uterus, and seminal vesicles in rats. It is also an inhibitor of the reductive pathway of Testosterone (T155000) metabolism.
References Hisao, N., et al.: Iyakuhin Kenkyu, 9, 307 (1978); Marberger, M., et al.: Investigative Urology, 13, 302 (1976);

Formula: C₂₀H₂₈O₃

Color and Shape: Neat

Molecular weight: 316.43

Ref: TR-G368270