CAS 213819-48-8: 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-, hydrochloride (1:1), (4S)-

Description: 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-, hydrochloride (1:1), (4S)-, is a complex organic compound characterized by its unique bicyclic structure that incorporates both pyrano and indolizino moieties. This compound features multiple functional groups, including a hydroxy group and an ethyl substituent, which contribute to its solubility and reactivity. The presence of a hydrochloride salt form indicates that it is a protonated species, enhancing its stability and solubility in aqueous environments. The stereochemistry denoted by (4S) suggests specific spatial arrangements of atoms, which can influence its biological activity and interactions. This compound may exhibit pharmacological properties, potentially acting as a therapeutic agent, although specific biological activities would require further investigation. Its CAS number, 213819-48-8, allows for precise identification in chemical databases, facilitating research and application in various fields, including medicinal chemistry and drug development.

Formula: C₂₅H₂₇N₃O₄·ClH

InChI: InChI=1S/C25H27N3O4.ClH/c1-4-25(31)19-11-21-22-17(12-28(21)23(29)18(19)13-32-24(25)30)15(9-10-26-14(2)3)16-7-5-6-8-20(16)27-22;/h5-8,11,14,26,31H,4,9-10,12-13H2,1-3H3;1H/t25-;/m0./s1

InChI key: InChIKey=SJKBXKKZBKCHET-UQIIZPHYSA-N

SMILES: Cl.O=C1OCC=2C(=O)N3C(=CC2C1(O)CC)C=4N=C5C=CC=CC5=C(C4C3)CCNC(C)C

Synonyms:

• (4S)-4-ethyl-4-hydroxy-11-{2-[(1-methylethyl)amino]ethyl}-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride
• (S)-4-Ethyl-4-hydroxy-11-(2-(isopropylamino)ethyl)-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride
• (S)-4-Ethyl-4-hydroxy-11-[2-(isopropylamino)ethyl]-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione hydrochloride
• 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-, hydrochloride (1:1), (4S)-
• 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-, monohydrochloride, (4S)-
• Belotecan hydrochloride
• Ckd 602

Camtobell hydrochloride

CAS: 213819-48-8

• Formula: C₂₅H₂₈ClN₃O₄
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 469.96052000000003

Belotecan hydrochloride

CAS: 213819-48-8

• Purity: 98%
• Molecular weight: 469.96g/mol

(S)-4-Ethyl-4-Hydroxy-11-(2-(Isopropylamino)Ethyl)-1H-Pyrano[3',4':6,7]Indolizino[1,2-B]Quinoline-3,14(4H,12H)-Dione Hydrochloride

CAS: 213819-48-8

• Purity: 97%
• Molecular weight: 469.96g/mol

Belotecan hydrochloride

CAS: 213819-48-8

Belotecan hydrochloride (CKD-602) is a synthetic water-soluble camptothecin derivative and topoisomerase I inhibitor with potential …

• Formula: C₂₅H₂₈ClN₃O₄
• Purity: 99.06% - ≥95%
• Color and Shape: Solid
• Molecular weight: 469.96

Belotecan HCl

CAS: 213819-48-8

• Formula: C₂₅H₂₇N₃O₄·HCl
• Molecular weight: 433.51 36.46

Belotecan Hydrochloride

CAS: 213819-48-8

Applications A novel camptothecin-derivative anti-tumor agent. CKD-602-related toxicities induced by IV infusion administration have not …

• Formula: C₂₅H₂₇N₃O₄·ClH
• Color and Shape: Neat
• Molecular weight: 469.96

Belotecan hydrochloride

CAS: 213819-48-8

Topoisomerase I inhibitor

• Formula: C₂₅H₂₈ClN₃O₄
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 469.96 g/mol