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CAS 2138814-32-9

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Found 2 products.
  • GSK3004774
    Biosynth
    + Info

    GSK3004774

    CAS:
    <p>GSK3004774 is a calcimimetic that binds to the extracellular Ca2+ channel receptor site. It has been shown to stimulate intracellular Ca2+ release in a dose-dependent manner and activate the enzyme adenylate cyclase, leading to an increase in intracellular cAMP. GSK3004774 also inhibits pro-inflammatory cytokines and regulatory T cells, as well as inflammatory cells in intestinal tissues. It is currently being investigated for its potential use in the treatment of hyperparathyroidism and inflammatory bowel disease.</p>
    Formula:C32H40N4O3
    Purity:Min. 95%
    Molecular weight:528.7 g/mol

    Ref: 3D-NKD81432

    5mg
    1,396.00€
    10mg
    2,175.00€
    25mg
    4,078.00€
    50mg
    6,524.00€
  • GSK3004774
    Targetmol
    + Info

    GSK3004774

    CAS:
    <p>GSK3004774 is a nonabsorbable agonist of CaSR (pEC50: 7.3, 6.6, and 6.5 for human, mouse, and rat CaSR). GSK3004774 shows an EC50 of 50 nM for human CaSR.</p>
    Formula:C32H40N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.68

    Ref: TM-T11493