CAS 2138861-99-9

N-Ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

Description:

N-Ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as amides, phenoxy, and pyrrolopyridine moieties. The presence of a fluorine atom suggests potential applications in medicinal chemistry, as fluorinated compounds often exhibit enhanced biological activity and metabolic stability. The compound's structure indicates it may possess significant lipophilicity due to the presence of aromatic rings and alkyl substituents, which can influence its solubility and permeability in biological systems. Additionally, the hydroxyl group may contribute to hydrogen bonding interactions, potentially affecting its pharmacokinetic properties. Overall, this compound's unique characteristics make it a candidate for further investigation in drug development, particularly in areas targeting specific biological pathways or conditions. However, detailed studies would be necessary to elucidate its specific properties and potential applications.

Formula: C₂₈H₃₀FN₃O₄

InChI: InChI=1S/C28H30FN3O4/c1-7-30-26(33)22-13-20-21(14-32(6)27(34)24(20)31-22)19-12-17(28(4,5)35)8-9-23(19)36-25-15(2)10-18(29)11-16(25)3/h8-14,31,35H,7H2,1-6H3,(H,30,33)

InChI key: InChIKey=OEDSFMUSNZDJFD-UHFFFAOYSA-N

SMILES: O=C1C2=C(C(=CN1C)C3=C(OC4=C(C)C=C(F)C=C4C)C=CC(C(C)(C)O)=C3)C=C(C(NCC)=O)N2

Synonyms:

• 1H-Pyrrolo[2,3-c]pyridine-2-carboxamide, N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-
• 1H-Pyrrolo[2,3-c]pyridine-2-carboxamide, N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-
• N-Ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide
• ABBV 744
• N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-h ydroxypropan-2-yl)phenyl]-6-methyl-7-oxo-1H,6H, 7H-pyrrolo[2,3-c]pyridine-2-carboxamide
• N-Ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide
• N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide
• CPD1639

N-Ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

CAS: 2138861-99-9

Formula: C₂₈H₃₀FN₃O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 491.5539

Ref: IN-DA01EO5M

N-Ethyl-4-(2-(4-Fluoro-2,6-Dimethylphenoxy)-5-(2-Hydroxypropan-2-Yl)Phenyl)-6-Methyl-7-Oxo-6,7-Dihydro-1H-Pyrrolo[2,3-C]Pyridine-2-Carboxamide

CAS: 2138861-99-9

N-Ethyl-4-(2-(4-Fluoro-2,6-Dimethylphenoxy)-5-(2-Hydroxypropan-2-Yl)Phenyl)-6-Methyl-7-Oxo-6,7-Dihydro-1H-Pyrrolo[2,3-C]Pyridine-2-Carboxamide

Purity: 99%

Molecular weight: 491.55g/mol

Ref: 54-PC108567

ABBV-744

CAS: 2138861-99-9

ABBV-744

Purity: ≥95%

Molecular weight: 491.55g/mol

Ref: 54-BUP15242

ABBV-744

CAS: 2138861-99-9

ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.

Formula: C₂₈H₃₀FN₃O₄

Purity: 97.03% - >99.99%

Color and Shape: Solid

Molecular weight: 491.55

Ref: TM-T4697

ABBV 744

Controlled Product

CAS: 2138861-99-9

Formula: C₂₈H₃₀FN₃O₄

Color and Shape: Neat

Molecular weight: 491.554

Ref: TR-A215290

ABBV 744

CAS: 2138861-99-9

BET bromodomain inhibitor selective for BDII

Formula: C₂₈H₃₀FN₃O₄

Purity: Min. 95%

Molecular weight: 491.55 g/mol

Ref: 3D-BA166477