CAS 213978-34-8

Cefdinir monohydrate

Description:

Cefdinir monohydrate is a broad-spectrum cephalosporin antibiotic used primarily to treat various bacterial infections. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a range of Gram-positive and Gram-negative bacteria. The chemical structure of cefdinir includes a beta-lactam ring, which is essential for its antibacterial activity. As a monohydrate, it contains one molecule of water per molecule of cefdinir, affecting its solubility and stability. Cefdinir is typically administered orally and is known for its favorable pharmacokinetic properties, including good absorption and a relatively long half-life, allowing for once or twice daily dosing. Common side effects may include gastrointestinal disturbances, such as diarrhea, and potential allergic reactions in sensitive individuals. It is important to note that cefdinir should be used judiciously to minimize the development of antibiotic resistance. Overall, cefdinir monohydrate is a valuable therapeutic agent in the treatment of infections, particularly in pediatric and adult populations.

Formula: C₁₄H₁₃N₅O₅S₂·H₂O

InChI: InChI=1S/C14H13N5O5S2.H2O/c1-2-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24)6-4-26-14(15)16-6;/h2,4,8,12,24H,1,3H2,(H2,15,16)(H,17,20)(H,22,23);1H2/b18-7-;/t8-,12-;/m1./s1

InChI key: InChIKey=QWUVJQSNISEEQI-KYIYMPJCSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\O)/C3=CSC(N)=N3)=O)C2=O)(SCC1C=C)[H].O

Synonyms:

• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-, monohydrate, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-, hydrate (1:1), (6R,7R)-
• Cefdinir monohydrate

Cefdinir

CAS: 213978-34-8

Antibiotics nesoi

Formula: C₁₄H₁₃N₅O₅S₂·H₂O

Color and Shape: Off-White Cream Crystalline Powder

Molecular weight: 395.03581

Ref: 45-1097614

Cefdinir monohydrate

CAS: 213978-34-8

Cefdinir monohydrate is a semi-synthetic, beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to PBPs.

Formula: C₁₄H₁₅N₅O₆S₂

Color and Shape: Solid

Molecular weight: 413.42

Ref: TM-T69873

Cefdinir monohydrate

CAS: 213978-34-8

Cefdinir monohydrate is a third-generation cephalosporin antibiotic, which is synthetically derived from cephalosporin C, a compound originally isolated from the fungus Acremonium. This antibiotic works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), which results in the interruption of peptidoglycan cross-linking. Consequently, this action leads to cell lysis and death of the bacterium.

Formula: C₁₄H₁₅N₅O₆S₂

Purity: Min. 95%

Molecular weight: 413.4 g/mol

Ref: 3D-NIA97834