CAS 2140-73-0
:1-Methylinosine
Description:
1-Methylinosine is a nucleoside derivative characterized by the presence of a methyl group at the N1 position of the purine base, inosine. It is a naturally occurring compound found in various biological systems, particularly in RNA. The molecular structure of 1-methylinosine consists of a ribose sugar linked to the purine base, which contributes to its role in cellular processes. This compound is involved in the regulation of gene expression and can influence various metabolic pathways. Its unique methylation pattern can affect the stability and function of RNA molecules, impacting protein synthesis and cellular signaling. 1-Methylinosine is also of interest in research related to epitranscriptomics, where modifications to RNA are studied for their biological significance. The CAS number 2140-73-0 uniquely identifies this compound in chemical databases, facilitating its study and application in various scientific fields, including biochemistry and molecular biology.
Formula:C11H14N4O5
InChI:InChI=1S/C11H14N4O5/c1-14-3-13-9-6(10(14)19)12-4-15(9)11-8(18)7(17)5(2-16)20-11/h3-5,7-8,11,16-18H,2H2,1H3/t5-,7-,8-,11-/m1/s1
InChI key:InChIKey=WJNGQIYEQLPJMN-IOSLPCCCSA-N
SMILES:O[C@H]1[C@H](N2C3=C(N=C2)C(=O)N(C)C=N3)O[C@H](CO)[C@H]1O
Synonyms:- 2140-73-0
- Inosine, 1-methyl-
- N<sup>1</sup>-Methylinosine
- 1-Methylinosine
- N1-Methylinosine
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Found 9 products.
(2R,3R,4S,5R)-2-(6-Hydroxy-1-Methyl-1H-Purin-9(2H)-Yl)-5-(Hydroxymethyl)Tetrahydrofuran-3,4-Diol
CAS:(2R,3R,4S,5R)-2-(6-Hydroxy-1-Methyl-1H-Purin-9(2H)-Yl)-5-(Hydroxymethyl)Tetrahydrofuran-3,4-DiolPurity:99%Molecular weight:282.25g/mol1-Methylinosine
CAS:Formula:C11H14N4O5Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:282.261-Methylinosine
CAS:<p>1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite.</p>Formula:C11H14N4O5Purity:99.7%Color and Shape:SolidMolecular weight:282.251-Methyl-Inosine
CAS:Controlled Product<p>Applications 1-Methyl-Inosine is a modified nucleoside which is present in higher concentrations in the urinary excretion of patients afflicted with breast cancer. It acts a a biomarker for diagnosis of the disease.<br>References Frickenschmidt, A. et al.: Biomark., 13, 435 (2008); Studzinska, S. et al.: J. Chrom. B. Tech. Biomed. Life Sci., 887, 93 (2012);<br></p>Formula:C11H14N4O5Color and Shape:NeatMolecular weight:282.25N1-Methylinosine
CAS:Controlled Product<p>N1-Methylinosine is a purine derivative that can be used as an imaging agent for the detection of autoimmune disorders. It has been shown to form stable complexes with proteins and human serum proteins, which have been detected in urine samples. N1-Methylinosine has also been used in clinical studies to measure disease activity in patients with rheumatoid arthritis and chronic kidney disease. This drug is activated by catalysis to produce a fluorescent product that can be detected using nmr spectroscopy. N1-Methylinosine is able to bind to autoantibodies and activate markers of chronic inflammation, such as nuclear factor kappa B (NF-κB) and tumor necrosis factor alpha (TNFα).<br>N1-Methylinosine has also been shown to inhibit breast cancer cell growth and reduce the severity of chronic kidney disease.</p>Formula:C11H14N4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:282.25 g/mol1-Methyl-Inosine-d3
CAS:Controlled Product<p>Applications 1-Methyl-Inosine-d3 is the isotope labelled analog of 1-Methyl-Inosine (M313600); a modified nucleoside which is present in higher concentrations in the urinary excretion of patients afflicted with breast cancer. It acts as a biomarker for diagnosis of the disease.<br>References Frickenschmidt, A. et al.: Biomark., 13, 435 (2008); Studzinska, S. et al.: J. Chrom. B. Tech. Biomed. Life Sci., 887, 93 (2012)<br></p>Formula:C11D3H11N4O5Color and Shape:NeatMolecular weight:285.271
