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CAS 2140807-58-3

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  • JBJ-07-149

    CAS:
    JBJ-07-149 is an inhibitor of EGFRL858R/T790M with an IC50 of 1.1 nM. It suppresses the proliferation of Ba/F3 cells with IC50 values of 4.9 μM when used alone, and 0.148 μM when combined with Cetuximab. Additionally, JBJ-07-149 can serve as a target protein ligand for synthesizing [DDC-01-163].
    Formula:C28H26N6O2S
    Color and Shape:Solid
    Molecular weight:510.61