CAS 21409-26-7

4-Anilino-N-phenethylpiperidine (ANPP)

Description:

4-Anilino-N-phenethylpiperidine (ANPP) is a synthetic chemical compound primarily recognized for its role as an intermediate in the synthesis of various psychoactive substances, particularly fentanyl analogs. It features a piperidine ring, which is a six-membered nitrogen-containing heterocycle, and is substituted with an aniline group and a phenethyl moiety. ANPP is characterized by its relatively complex structure, which contributes to its pharmacological properties. The compound is typically a white to off-white crystalline solid and is soluble in organic solvents. Due to its structural similarity to other opioids, ANPP exhibits affinity for opioid receptors, which can lead to significant analgesic effects. However, it is also associated with potential for abuse and dependence, necessitating careful regulation. The compound is not widely used in clinical settings but is of interest in research and forensic contexts. As with many synthetic opioids, safety and handling precautions are essential due to its potency and the risks associated with opioid exposure.

Formula: C₁₉H₂₄N₂

InChI: InChI=1S/C19H24N2/c1-3-7-17(8-4-1)11-14-21-15-12-19(13-16-21)20-18-9-5-2-6-10-18/h1-10,19-20H,11-16H2

InChI key: InChIKey=ZCMDXDQUYIWEKB-UHFFFAOYSA-N

SMILES: N(C1CCN(CCC2=CC=CC=C2)CC1)C3=CC=CC=C3

Synonyms:

• 1-(2-Phenylethyl)-4-phenylaminopiperidine
• 1-Phenethyl-N-phenylpiperidin-4-amine
• 4-Anilino-1-(2-phenethyl)piperidine
• 4-Anilino-1-(β-phenethyl)piperidine
• 4-Anilino-1-phenethylpiperidine
• 4-Piperidinamine, N-phenyl-1-(2-phenylethyl)-
• 4-anilino-N-fenetilpiperidina (ANPP)
• 4Anpp
• ANPP, N-phenyl-1-(2-phenylethyl)piperidin-4-amine
• Depropionylfentanyl
• N-Phenyl-1-(2-phenylethyl)-4-piperidinamine
• N-[1-(2-Phenylethyl)-4-piperidinyl]aniline
• Piperidine, 4-anilino-1-phenethyl-
• Fentanyl Related Compound E CII (10 mg) (N-Phenyl-1-(2-phenylethyl)-4-piperidinamine)
• N-(1-phenyl-piperidin-4-yl)-aniline
• TBC-5487
• N-[1-(2-Phenylethyl)-4-piperidinyl]benzenamine
• Fentanyl Related CoMpound E CII
• (1-PHENETHYL-PIPERIDIN-4-YL)-PHENYL-AMINE
• N-PHENYL-1-(2-PHENYLETHYL) PIPERIDIN-4-AMINE
• 4-ANPP
• N-(1-PHENETHYL-PIPERIDIN-4-YL)-ANILINE
• N-Phenyl-N’-[1-(2-phenylethyl)]-4-piperidine
• 4-AMinophenyl-1-phenethylpiperidine (Fentanyl IMpurity)
• Discontinued See: A625875

N-Phenyl-1-(2-phenylethyl)piperidin-4-amine

Controlled Product

CAS: 21409-26-7

Color and Shape: Neat

Ref: 61-FOR0528.04

N-Phenyl-1-(2-phenylethyl)piperidin-4-amine

Controlled Product

CAS: 21409-26-7

Formula: C₁₉H₂₄N₂

Color and Shape: Neat

Molecular weight: 280.41

Ref: 86-MM0528.04

4-Aminophenyl-1-phenethylpiperidine

Controlled Product

CAS: 21409-26-7

Impurity Fentanyl Impurity D / Fentanyl USP Related Compound E
Applications 4-Aminophenyl-1-phenethylpiperidine is a metabolite of 3H-Fentanyl (F274990), which is used as an analgesic.Controlled Substance.
References Labroo, R., et al.: Drug Metab., Disposition, 25, 1072 (1997); Zernig, G., et al.: Life Sci., 57, 2113 (1995); Bot, G., et al.: J. Pharmacol. Exper. Therap., 285, 1207 (1998);

Formula: C₁₉H₂₄N₂

Color and Shape: Neat

Molecular weight: 280.41

Ref: TR-A625875

4-ANPP

Controlled Product

CAS: 21409-26-7

4-ANPP is a solution in acetonitrile that is commonly used in the production of biodiesel. It is also used as an intermediate for the synthesis of various compounds, including β-ionone and hydroxyapatite. 4-ANPP has been shown to have controlled release properties, making it suitable for use in controlled-release products. It can be used as a phosphatase inhibitor, preventing the breakdown of phosphates in biological systems. Additionally, 4-ANPP has been found to enhance biomass production and improve cell growth in certain applications. Its unique properties make it a versatile compound for various industries, including pharmaceuticals, agriculture, and research.

Formula: C₁₉H₂₄N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 280.41 g/mol

Ref: 3D-IP17824

4-Aminophenyl-1-phenethylpiperidine (Fentanyl Impurity) (1mg/ml in Acetonitrile)

Controlled Product

CAS: 21409-26-7

Formula: C₁₉H₂₄N₂

Color and Shape: Colourless

Molecular weight: 280.41

Ref: TR-KIT2895

Fentanyl Related Compound E CII (N-Phenyl-1-(2-phenylethyl)-4-piperidinamine)

Controlled Product

CAS: 21409-26-7

4-anilino-n-phenethylpiperidine (anpp)

Formula: C₁₉H₂₄N₂

Color and Shape: White Light Brown Crystalline Powder

Molecular weight: 280.19395

Ref: 45-1269957