CAS 21411-53-0: Virginiamycin M1

Description: Virginiamycin M1 is a macrolide antibiotic that is derived from the fermentation of the bacterium *Streptomyces virginiae*. It is primarily used in veterinary medicine as a growth promoter and to treat certain bacterial infections in livestock. The compound exhibits a broad spectrum of antimicrobial activity, particularly against Gram-positive bacteria, and is often used in combination with other antibiotics to enhance efficacy and reduce resistance development. Virginiamycin M1 functions by inhibiting protein synthesis in bacteria, thereby preventing their growth and reproduction. It is known for its relatively low toxicity in animals when used at recommended doses. Additionally, it has been studied for its potential effects on human health, particularly regarding antibiotic resistance. The substance is typically administered via feed or water in agricultural settings. As with many antibiotics, careful management is essential to mitigate the risk of resistance and ensure the sustainability of its use in animal husbandry.

Formula: C₂₈H₃₅N₃O₇

InChI: InChI=1/C28H35N3O7/c1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b7-5+,10-9+,18-13+/t19-,20-,26-/m1/s1

InChI key: InChIKey=DAIKHDNSXMZDCU-FQTGFAPKSA-N

SMILES: O=C1OC(C(C=CC(=O)NCC=CC(=CC(O)CC(=O)CC2=NC(=CO2)C(=O)N3C1=CCC3)C)C)C(C)C

Synonyms:

• (3R,4R,5E,10E,12E,14S)-14-hydroxy-4,12-dimethyl-3-(propan-2-yl)-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
• (3R,4R,5E,10E,12E,14S)-8,9,14,15,24,25-Hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
• (3R,4R,5E,14S)-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
• (3R,4R,5Z,10Z,12Z,14S)-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
• (3S,4S,5Z,10Z,12Z,14R)-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
• 14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
• 3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 8,9,14,15,24,25-hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S)-
• 8,9,14,15,24,25-Hexahydro-14-hydroxy-3-isopropyl-4,12-dimethyl-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
• 8,9,14,15,24,25-Hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
• Antibiotic PA 114A
• Antibiotic PA 114A1
• Factor M
• Factor M (antibiotic)
• Mikamycin A
• Nsc 244426
• Nsc 87432
• Ostreogrycin a
• Pa 114A
• Pristinamycin II
• Pristinamycin II_A
• Rp 12536
• Staphylomycin M₁
• Streptogramin A
• Vernamycin A
• Virginiamycin M₁
• Virginiamycin factor M1
• [3R-(3R*,4R*,5E,10E,12E,14S*)]-8,9,14,15,24,25-Hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
• Virginiamycin M1

Virginiamycin M

CAS: 21411-53-0

• Formula: C₂₈H₃₅N₃O₇
• Purity: ≥ 95.0%
• Color and Shape: Off-white to pale yellow powder
• Molecular weight: 525.6

Virginiamycin M1

CAS: 21411-53-0

Virginiamycin M1 (Pristinamycin IIA) is a macrocyclic lactone peptide antibiotic and is a member of …

• Formula: C₂₈H₃₅N₃O₇
• Purity: 98.57%
• Color and Shape: Solid
• Molecular weight: 525.59

Virginiamycin M1 (Pristinamycin IIA)

CAS: 21411-53-0

• Formula: C₂₈H₃₅N₃O₇
• Color and Shape: Off-White Solid
• Molecular weight: 525.61

Virginiamycin M1

CAS: 21411-53-0

• Formula: C₂₈H₃₅N₃O₇
• Purity: By hplc: 98.25% (Typical Value in Batch COA)
• Color and Shape: slightly yellow powder
• Molecular weight: 525.59g/mol

Virginiamycin M1

CAS: 21411-53-0

• Purity: ≥98%
• Molecular weight: 525.59g/mol

Virginiamycin M1

CAS: 21411-53-0

• Formula: C₂₈H₃₅N₃O₇
• Color and Shape: Neat
• Molecular weight: 525.59

Virginiamycin M1 (~90%)

CAS: 21411-53-0

Applications Macrolactone antibiotic. Antibacterial; growth promotant. This compound is a contaminant of emerging concern (CECs). …

• Formula: C₂₈H₃₅N₃O₇
• Purity: ~90%
• Color and Shape: Light Yellow To Beige
• Molecular weight: 525.59

Virginiamycin M1-d2

CAS: 21411-53-0

Stability Light Sensitive Applications Virginiamycin M1-d2 is the labelled form of Virginiamycin M1 (V673810), which …

• Formula: C₂₈D₂H₃₃N₃O₇
• Purity: >90%
• Color and Shape: Light Yellow
• Molecular weight: 525.59

Virginiamycin M1 (200 ug/mL in Methanol) (~90%)

CAS: 21411-53-0

• Formula: C₂₈H₃₅N₃O₇
• Purity: ~90%
• Color and Shape: Single Solution
• Molecular weight: 525.59

Virginiamycin M1

CAS: 21411-53-0

Inhibitor of protein synthesis; streptogramin

• Formula: C₂₈H₃₅N₃O₇
• Purity: Min. 95%
• Molecular weight: 525.59 g/mol