CAS 21414-41-5

Glucoraphanin

Description:

Glucoraphanin is a naturally occurring glucosinolate, primarily found in cruciferous vegetables such as broccoli and Brussels sprouts. It is a sulfur-containing compound that plays a significant role in the plant's defense mechanisms against pests and diseases. Glucoraphanin is notable for its potential health benefits, particularly its role as a precursor to sulforaphane, a compound known for its antioxidant and anti-cancer properties. When glucoraphanin is hydrolyzed by the enzyme myrosinase, it converts into sulforaphane, which has been studied for its ability to activate detoxification enzymes and protect against oxidative stress. The compound is water-soluble and has a relatively stable structure, although it can be affected by cooking methods that denature myrosinase. Research suggests that regular consumption of glucoraphanin-rich foods may contribute to improved health outcomes, including reduced risk of certain chronic diseases. Its CAS number, 21414-41-5, is used for identification in chemical databases and regulatory contexts.

Formula: C₁₂H₂₃NO₁₀S₃

InChI: InChI=1S/C12H23NO10S3/c1-25(18)5-3-2-4-8(13-23-26(19,20)21)24-12-11(17)10(16)9(15)7(6-14)22-12/h7,9-12,14-17H,2-6H2,1H3,(H,19,20,21)/t7-,9-,10+,11-,12+,25?/m1/s1

InChI key: InChIKey=GMMLNKINDDUDCF-SISVVIKZSA-N

SMILES: S(C(CCCCS(C)=O)=NOS(=O)(=O)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Synonyms:

• 1-S-[(1E)-5-(methylsulfinyl)-N-(sulfonatooxy)pentanimidoyl]-1-thio-beta-D-glucopyranose
• 4-Methylsulfinylbutyl glucosinolate
• Ccris 9055
• Glucopyranose, 1-thio-, 1-[5-(methylsulfinyl)valerohydroximate] NO-(hydrogen sulfate), β-<span class="text-smallcaps">D</span>-
• Glucorafanin
• Sulforaphane glucosinolate
• beta-D-Glucopyranose, 1-thio-, 1-(5-(methylsulfinyl)-N-(sulfooxy)pentanimidate)
• β-<span class="text-smallcaps">D</span>-Glucopyranose, 1-thio-, 1-[5-(methylsulfinyl)-N-(sulfooxy)pentanimidate]
• β-D-Glucopyranose, 1-thio-, 1-[5-(methylsulfinyl)-N-(sulfooxy)pentanimidate]
• Glucoraphanin
• Glucopyranose, 1-thio-, 1-[5-(methylsulfinyl)valerohydroximate] NO-(hydrogen sulfate), β-D-

Glucoraphanin potassium salt

CAS: 21414-41-5

Glucoraphanin potassium salt analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₂H₂₂NO₁₀S₃K

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 475.59

Ref: 11-2509S

Glucoraphanin

CAS: 21414-41-5

Formula: C₁₂H₂₃NO₁₀S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 437.5067

Ref: IN-DA00BE59

Glucoraphanin

CAS: 21414-41-5

Formula: C₁₂H₂₂KNO₁₀S₃

Purity: ≥ 98.0%

Color and Shape: White to light brown powder

Molecular weight: 475.58

Ref: 7W-GY0919

Glucoraphanin

CAS: 21414-41-5

Glucoraphanin

Purity: ≥98%

Molecular weight: 437.51g/mol

Ref: 54-BUP01430

Glucoraphanin

CAS: 21414-41-5

Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, it has antioxidant activity, it induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver. Glucoraphanin can ameliorates obesity and insulin resistance through adipose tissue browning and reduction of metabolic endotoxemia in mice. Glucoraphanin and Glucoerucin effectively act as antagonists for the aryl hydrocarbon receptor, and this may contribute to their established chemoprevention potency.

Formula: C₁₂H₂₃NO₁₀S₃

Purity: 95%~99%

Molecular weight: 437.51

Ref: BP-BP0676

Glucoraphanin

CAS: 21414-41-5

Glucoraphanin, the precursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, has antioxidant activity.

Formula: C₁₂H₂₃NO₁₀S₃

Purity: 98.86% - 99.64%

Color and Shape: Solid

Molecular weight: 437.51

Ref: TM-TQ0212

Glucoraphanin potassium salt

CAS: 21414-41-5

Natural glycoside

Formula: C₁₂H₂₂NO₁₀S₃K

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 475.6

Ref: 5G-89215

Glucoraphanin

CAS: 21414-41-5

Applications Glucoraphanin is a natural glycoinsolate found in cruciferous vegetables. Glucophanin (Sulforaphane), is a bioactive component in brocolli and is digested by gut bacteria to produce chemopreventive agents.
References Luang-In, V. et al.: Mol. Nutr. Food. Res., 58, 875 (2014); Blazevic, I. et al.: Nat. Prod. Comm., 8, 1463 (2013);

Formula: C₁₂H₂₃NO₁₀S₃

Color and Shape: Off-White

Molecular weight: 437.51

Ref: TR-G450250

Glucoraphanin Sodium-d5

Controlled Product

CAS: 21414-41-5

Applications Glucoraphanin-d5 is the isotope labelled analog of Glucoraphanin. Glucoraphanin is a natural glycoinsolate found in cruciferous vegetables. Glucophanin (Sulforaphane), is a bioactive component in brocolli and is digested by gut bacteria to produce chemopreventive agents.
References Luang-In, V. et al.: Mol. Nutr. Food. Res., 58, 875 (2014); Blazevic, I. et al.: Nat. Prod. Comm., 8, 1463 (2013);

Formula: C₁₂D₅H₁₇NNaO₁₀S₃

Color and Shape: Neat

Molecular weight: 464.519

Ref: TR-G450252

Glucoraphanin

CAS: 21414-41-5

Glucoraphanin is a bioactive compound, specifically a glucosinolate, which is a secondary metabolite derived from cruciferous vegetables, predominantly broccoli. Its mode of action involves conversion into sulforaphane through the enzyme myrosinase, which can occur during digestion or when the plant tissue is damaged. Sulforaphane then acts as a potent inducer of phase II detoxification enzymes and modulates antioxidant responses via the activation of the Nrf2 (nuclear factor erythroid 2-related factor 2) pathway.

Formula: C₁₂H₂₃NO₁₀S₃

Purity: Min. 95%

Molecular weight: 437.51 g/mol

Ref: 3D-XG184206

Glucoraphanin Potassium Salt Reference Standard Grade, 90%

CAS: 21414-41-5

Formula: C₁₂H₂₂KNO₁₀S₃

Purity: min. 90%

Color and Shape: White to off white, Hygroscopic  compound

Molecular weight: 475.59

Ref: SR-74587

Glucoraphanin Potassium Salt (Contains up to ~15% Inorganics)

Controlled Product

CAS: 21414-41-5

Applications Potassium salt of Glucoraphanin (G450250) is a natural glycoinsolate found in cruciferous vegetables. Glucophanin (Sulforaphane), is a bioactive component in brocolli and is digested by gut bacteria to produce chemopreventive agents.
References Luang-In, V. et al.: Mol. Nutr. Food. Res., 58, 875 (2014); Blazevic, I. et al.: Nat. Prod. Comm., 8, 1463 (2013);

Formula: C₁₂H₂₂NO₁₀S₃·K

Color and Shape: Off-White

Molecular weight: 475.60

Ref: TR-G450255

Glucoraphanin

CAS: 21414-41-5

Glucoraphanin is a chemoprotective compound, which is a naturally occurring glucosinolate found predominantly in cruciferous vegetables, with broccoli being a primary source. It undergoes conversion by the enzyme myrosinase to produce sulforaphane, a potent antioxidative agent. This process is facilitated by mastication and microbial action in the gut, leading to activation of pathways that upregulate detoxification enzymes and confer protective effects against oxidative stress.

Formula: C₁₂H₂₃NO₁₀S₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 437.51 g/mol

Ref: 3D-FG159554