CAS 21416-43-3

1-[3-(aminooxy)-3-oxopropyl]pyrimidine-2,4(1H,3H)-dione

Description:

1-[3-(Aminooxy)-3-oxopropyl]pyrimidine-2,4(1H,3H)-dione, with the CAS number 21416-43-3, is a chemical compound characterized by its pyrimidine core, which is a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3. This compound features an aminooxy group, which is known for its ability to form covalent bonds with carbonyl groups, making it useful in various biochemical applications, particularly in the modification of biomolecules. The presence of the oxopropyl group indicates that it has a ketone functional group, contributing to its reactivity. The compound is likely to exhibit polar characteristics due to the presence of functional groups, which can influence its solubility in polar solvents. Additionally, its structure suggests potential biological activity, making it of interest in medicinal chemistry and drug development. Overall, this compound's unique functional groups and structural features position it as a versatile molecule in chemical research and applications.

Formula: C₇H₉N₃O₄

InChI: InChI=1/C7H9N3O4/c8-14-6(12)2-4-10-3-1-5(11)9-7(10)13/h1,3H,2,4,8H2,(H,9,11,13)

InChI key: InChIKey=FACUYWPMDKTVFU-BYPYZUCNSA-N

SMILES: C([C@@H](C(O)=O)N)N1C(=O)NC(=O)C=C1

Synonyms:

• 1(2H)-Pyrimidinepropanoic acid, α-amino-3,4-dihydro-2,4-dioxo-, (S)-
• 1(2H)-Pyrimidinepropionic acid, α-amino-3,4-dihydro-2,4-dioxo-, (S)-
• L-Willardiine
• 1(2H)-Pyrimidinepropanoic acid, α-amino-3,4-dihydro-2,4-dioxo-, (αS)-
• (αS)-α-Amino-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
• (S)-2-Amino-3-[2,4-dioxo-3,4-dihydropyrimidine-1(2H)-yl]propanoic acid
• 3-(Uracil-1-yl)-L-alanine
• S(-)-α-Amino--3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
• (2S)-2-Amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine-1-yl)propionic acid
• willardiine
• 3-[(2,4-Dioxo-1,2,3,4-tetrahydropyrimidine)-1-yl]-L-alanine
• C03584
• Willardine
• S(-)-WILLARDIINE AMPA/KAINATE AGONIST
• S(-)-WILLARDIINE
• S(-)-ALPHA-AMINO-3,4-DIHYDRO-2,4-DIOXO-1(2H)-PYRIMIDINEPROPANOIC ACID
• (-)-WILLARDIINE

(S)-Willardiine

CAS: 21416-43-3

(S)-Willardiine

Purity: ≥98%

Molecular weight: 199.16g/mol

Ref: 54-BUP14425

(S)-Willardiine

CAS: 21416-43-3

M03883 - (S)-Willardiine

Formula: C₇H₉N₃O₄

Purity: >98%

Color and Shape: Solid

Molecular weight: 199.166

Ref: 10-M03883

(S)-Willardiine

CAS: 21416-43-3

(S)-Willardiine is a sodium salt that belongs to the group of pharmacological agents. It is used as a chemical intermediate, but has been found to have some biological properties. In vivo studies in rats have shown that (S)-willardiine inhibits the release of glutamate and GABA in the cortex and hippocampus, which may be related to its ability to increase locomotor activity. Disulfide bond formation is required for biological activity, which has been observed using human serum. The structure of (S)-willardiine was determined by x-ray crystallography at 1.5 Å resolution, revealing that it contains an asymmetric unit consisting of one molecule each of (S)-willardiine and sodium chloride.

Formula: C₇H₉N₃O₄

Purity: Min. 95%

Molecular weight: 199.17 g/mol

Ref: 3D-WAA41643

(S)-Willardiine

CAS: 21416-43-3

(S)-Willardiine (L-willardiine) is present in the seeds of Acacia and Mimosa. (S)-Willardiine is an AMPA/kainate receptor agonist (EC50 = 44.8 μM).

Formula: C₇H₉N₃O₄

Purity: 99.85%

Color and Shape: Solid

Molecular weight: 199.16

Ref: TM-T13456