CAS 21416-67-1: Razoxane

Description: Razoxane, with the CAS number 21416-67-1, is a chemical compound primarily recognized for its role as a pharmaceutical agent, particularly in cancer treatment. It is classified as a hydroxamic acid derivative and functions as a topoisomerase inhibitor, which interferes with DNA replication and repair processes in cancer cells. This mechanism makes it a potential therapeutic option in oncology, particularly for certain types of tumors. Razoxane is also noted for its ability to reduce the cardiotoxic effects associated with some chemotherapeutic agents, thereby providing a protective effect on heart tissue during cancer treatment. In terms of physical properties, Razoxane is typically a white to off-white solid, soluble in water and various organic solvents, which facilitates its formulation in medicinal applications. Its chemical structure includes functional groups that contribute to its biological activity and solubility. As with many pharmaceuticals, the use of Razoxane is subject to specific dosing regimens and potential side effects, necessitating careful clinical consideration.

Formula: C₁₁H₁₆N₄O₄

InChI: InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)

InChI key: InChIKey=BMKDZUISNHGIBY-UHFFFAOYSA-N

SMILES: O=C1NC(=O)CN(C1)CC(N2CC(=O)NC(=O)C2)C

Synonyms:

• (±)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane
• (±)-1,2-Bis(3,5-dioxopiperazinyl)propane
• 1,2-Bis(3,5-dioxo-1-piperazinyl)propane
• 2,6-Piperazinedione, 4,4'-(1-Methyl-1,2-Ethanediyl)Bis-
• 2,6-Piperazinedione, 4,4′-propylenedi-
• 21416-67-1
• 4,4'-Propane-1,2-diyldipiperazine-2,6-dione
• 4,4'-Propane-1,3-Diyldipiperazine-2,6-Dione
• 4,4'-Propylenebis(Piperazine-2,6-Dione)
• 4,4′-(1-Methyl-1,2-ethanediyl)bis[2,6-piperazinedione]
• 4,4′-Propylenebis(2,6-piperazinedione)
• 4,4′-Propylenedi(2,6-piperazinedione)
• Ici 59118
• Icrf 159
• NSC 129943
• Razoxin
• Tepirone
• Troxozone

4,4'-propylenebis(piperazine-2,6-dione)

CAS: 21416-67-1

• Formula: C₁₁H₁₆N₄O₄
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 268.2691

Razoxane

CAS: 21416-67-1

• Purity: 99.41%
• Molecular weight: 268.27g/mol

4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)

CAS: 21416-67-1

• Purity: 95.0%
• Molecular weight: 268.27301025390625

Razoxane

CAS: 21416-67-1

Razoxane is used as an antimitotic agent with immunosuppressive properties.

• Formula: C₁₁H₁₆N₄O₄
• Purity: 99.42%
• Color and Shape: Solid
• Molecular weight: 268.27

4,4'-propylenebis(piperazine-2,6-dione)

CAS: 21416-67-1

4,4'-propylenebis(piperazine-2,6-dione) is a cytotoxic agent that inhibits the proliferation of cancer cells by interfering with …

• Formula: C₁₁H₁₆N₄O₄
• Purity: Min. 95%
• Molecular weight: 268.27 g/mol