CAS 214287-98-6

(E)-4(S)-(2-Cyclopropylvinyl)-5,6-difluoro-4-(trifluoromethyl)-3,4-dihydro-1H-quinazolin-2-one

Description:

(E)-4(S)-(2-Cyclopropylvinyl)-5,6-difluoro-4-(trifluoromethyl)-3,4-dihydro-1H-quinazolin-2-one, with CAS number 214287-98-6, is a synthetic organic compound characterized by its complex molecular structure, which includes a quinazolinone core. This compound features multiple fluorine substituents, contributing to its unique chemical properties, such as increased lipophilicity and potential bioactivity. The presence of a cyclopropylvinyl group enhances its structural diversity, which may influence its interactions with biological targets. The compound's stereochemistry, indicated by the (E) and (S) designations, suggests specific spatial arrangements that can affect its reactivity and binding affinity in biological systems. Typically, compounds of this nature are investigated for their potential pharmaceutical applications, particularly in the development of novel therapeutic agents. The fluorinated groups may also enhance metabolic stability and alter pharmacokinetic profiles. Overall, this compound exemplifies the intricate design often employed in medicinal chemistry to optimize biological activity and selectivity.

Formula: C₁₄H₁₁F₅N₂O

InChI: InChI=1/C14H11F5N2O/c15-8-3-4-9-10(11(8)16)13(14(17,18)19,21-12(22)20-9)6-5-7-1-2-7/h3-7H,1-2H2,(H2,20,21,22)/b6-5+/t13-/m0/s1

Synonyms:

• DPC-082
• (4S)-4-[(E)-2-cyclopropylethenyl]-5,6-difluoro-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one

DPC-082

CAS: 214287-98-6

DPC-082 is a potent reverse transcriptase inhibitor effective against wild-type HIV-1 and various mutants.

Formula: C₁₄H₁₁F₅N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 318.24

Ref: TM-T27201