CAS 21438-66-4

Glycyl-N-2-naphthalenyl-L-phenylalaninamide

Description:

Glycyl-N-2-naphthalenyl-L-phenylalaninamide, identified by its CAS number 21438-66-4, is a synthetic compound that belongs to the class of peptides and amides. It features a glycine moiety linked to a phenylalanine derivative, which is further substituted with a naphthalene group. This structure contributes to its potential biological activity, particularly in the context of medicinal chemistry and drug design. The compound may exhibit properties such as moderate solubility in organic solvents and varying solubility in aqueous environments, influenced by its hydrophobic naphthalene component. Its molecular structure suggests potential interactions with biological targets, making it of interest in pharmacological studies. Additionally, the presence of aromatic rings may impart unique optical properties, which could be useful in analytical applications. As with many synthetic compounds, the stability, reactivity, and specific interactions of Glycyl-N-2-naphthalenyl-L-phenylalaninamide would depend on the surrounding conditions, including pH and temperature. Further research is necessary to fully elucidate its characteristics and potential applications in various fields.

Formula: C₂₁H₂₁N₃O₂

InChI: InChI=1S/C21H21N3O2/c22-14-20(25)24-19(12-15-6-2-1-3-7-15)21(26)23-18-11-10-16-8-4-5-9-17(16)13-18/h1-11,13,19H,12,14,22H2,(H,23,26)(H,24,25)/t19-/m0/s1

InChI key: InChIKey=YABDXPBHLDPMOA-IBGZPJMESA-N

SMILES: N(C([C@H](CC1=CC=CC=C1)NC(CN)=O)=O)C2=CC3=C(C=C2)C=CC=C3

Synonyms:

• (2S)-2-[(2-Aminoacetyl)amino]-N-naphthalen-2-yl-3-phenylpropanamide
• <span class="text-smallcaps">L</span>-Phenylalaninamide, glycyl-N-2-naphthalenyl-
• Alaninamide, glycylphenyl-N-2-naphthyl-, <span class="text-smallcaps">L</span>-
• Glycyl-<span class="text-smallcaps">L</span>-phenylalanine 2-naphthylamide
• Glycyl-<span class="text-smallcaps">L</span>-phenylalanine-β-naphthylamide
• Glycyl-N-2-naphthalenyl-<span class="text-smallcaps">L</span>-phenylalaninamide
• H-Gly-Phe-.beta.NA
• Hydrocinnamamide, α-(2-aminoacetamido)-N-2-naphthyl-, <span class="text-smallcaps">L</span>-
• glycyl-N-naphthalen-2-yl-L-phenylalaninamide
• glycyl-N-naphthalen-2-ylphenylalaninamide
• Hydrocinnamamide, α-(2-aminoacetamido)-N-2-naphthyl-, L-
• Glycyl-N-2-naphthalenyl-L-phenylalaninamide
• Glycyl-L-phenylalanine 2-naphthylamide
• L-Phenylalaninamide, glycyl-N-2-naphthalenyl-

Gly-Phe-β-naphthylamide

CAS: 21438-66-4

Formula: C₂₁H₂₁N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 347.4103

Ref: IN-DA00C2CL

Gly-Phe β-naphthylamide

CAS: 21438-66-4

Formula: C₂₁H₂₁N₃O₂

Purity: ≥ 95.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 347.41

Ref: 7W-GX9084

Gly-Phe-β-naphthylamide

CAS: 21438-66-4

Gly-Phe-β-naphthylamide

Purity: 98%

Ref: 54-OR1036700

Gly-Phe-β-naphthylamide

CAS: 21438-66-4

Purity: 98%

Molecular weight: 347.418

Ref: 10-F987745

H-Gly-Phe-bNA

CAS: 21438-66-4

H-Gly-Phe-bNA is a dinucleotide phosphate that is activated by phosphatase to form an active nucleotide. This nucleotide inhibits the polymerase chain reaction (PCR) by binding to the template DNA strand and preventing the addition of nucleotides by the DNA polymerase. The monoclonal antibody recognizes H-Gly-Phe-bNA and binds it in a radioactive assay, inhibiting the activity of this dinucleotide phosphate. Radiation causes H-Gly-Phe-bNA to produce reactive oxygen species, which can induce DNA damage or cause cell death. This nucleotide also has an acidic pH optimum for its activity, making it useful in acidic environments such as lysosomes. H-Gly-Phe-bNA also binds to cation channels and is localized primarily in the cytosol, with some found in mitochondria or microsomes. It also has a high affinity for calcium ions

Formula: C₂₁H₂₁N₃O₂

Purity: Min. 95%

Molecular weight: 347.41 g/mol

Ref: 3D-FG110667

H-Gly-Phe-βNA

CAS: 21438-66-4

GF-βNA (GPN), standard substrate for assays of dipeptidyl aminopeptidase I (cathepsin C). GPN causes osmotic permeabilization of lysosomes due to intralysosomal hydrolysis by cathepsin C.

Formula: C₂₁H₂₁N₃O₂

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 347.42

Ref: 01-4001208