CAS 21446-46-8

Pyridinium, 1-methyl-3-[(2S)-1-methyl-2-pyrrolidinyl]-, iodide (1:1)

Description:

Pyridinium, 1-methyl-3-[(2S)-1-methyl-2-pyrrolidinyl]-, iodide (1:1), with the CAS number 21446-46-8, is a quaternary ammonium salt characterized by its pyridinium and pyrrolidine components. This compound typically exhibits a white to off-white crystalline appearance and is soluble in polar solvents, such as water and alcohols, due to its ionic nature. The presence of the iodide ion contributes to its stability and solubility. As a quaternary ammonium compound, it may exhibit surfactant properties and can interact with biological membranes, making it of interest in pharmacological and biochemical applications. The stereochemistry of the pyrrolidine moiety, specifically the (2S) configuration, can influence its biological activity and interactions. Additionally, this compound may be sensitive to moisture and should be stored in a dry environment to maintain its integrity. Overall, its unique structural features and properties make it a subject of interest in various fields, including medicinal chemistry and organic synthesis.

Formula: C₁₁H₁₇N₂·I

InChI: InChI=1S/C11H17N2.HI/c1-12-7-3-5-10(9-12)11-6-4-8-13(11)2;/h3,5,7,9,11H,4,6,8H2,1-2H3;1H/q+1;/p-1/t11-;/m0./s1

InChI key: InChIKey=DYAGPCQOMOCCFX-MERQFXBCSA-M

SMILES: CN1[C@H](C2=C[N+](C)=CC=C2)CCC1.[I-]

Synonyms:

• (S)-N-Methylnicotinium iodide
• 1-Methyl-3-(1-Methylpyrrolidin-2-Yl)Pyridinium Iodide
• 1-Methyl-3-(1-methyl-2-pyrrolidinyl)pyridinium iodide
• 1-Methyl-3-[(2S)-1-methylpyrrolidin-2-yl]pyridin-1-ium iodide
• 1-Methylnicotinium iodide
• 1-methyl-3-[(2S)-1-methylpyrrolidin-2-yl]pyridinium iodide
• Iodure de iso-monomethylnicotinium
• Iodure de iso-monomethylnicotinium [French]
• Isomonomethyl nicotinium iodide
• N-Methylnicotinium iodide
• Nicotine N-methiodide
• Nicotine isomethiodide
• Nicotine, methiodide (monomethyl)
• Nicotinium, 1-methyl-, iodide
• Pyridinium, 1-methyl-3-(1-methyl-2-pyrrolidinyl)-, iodide, (-)-
• Pyridinium, 1-methyl-3-(1-methyl-2-pyrrolidinyl)-, iodide, (S)-
• Pyridinium, 1-methyl-3-[(2S)-1-methyl-2-pyrrolidinyl]-, iodide

N-methylnicotinium Iodide

CAS: 21446-46-8

Formula: C₁₁H₁₇N₂·I

Molecular weight: 177.27 126.91

Ref: 4Z-N-0662

(S)-1-Methylnicotinium Iodide

Controlled Product

CAS: 21446-46-8

Applications (S)-1-Methylnicotinium Iodide exhibits antinociceptive activity. A nicotinic receptor antagonist and a metabolite of Nicotine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Aceto, M. D., et al.: Br. J. Pharmacol., 79, 869-876 (1983); Wilkins, L. H., et al.: J. Pharm. Exp. Ther., 304, 400-410 (2003); Seeman, J.I. and Whidby, J.F.: J. Org. Chem., 41, 24, 3824 (1976), Oldendorf, W.H., et al.: Proc. Natl. Acad. Sci., USA, 90, 307 (1993)

Formula: C₁₁H₁₇N₂·I

Color and Shape: Neat

Molecular weight: 304.17

Ref: TR-M323275

(S)-1-Methylnicotinium iodide

CAS: 21446-46-8

(S)-1-Methylnicotinium iodide is a methylated compound that acts as a pressor agent. It is also used in the treatment of anesthetized patients and those with pyridine poisoning. The molecule is monomethyl, which gives it a high affinity for the nicotinic acetylcholine receptor in the brain. This leads to increased blood pressure and heart rate, which are due to the activation of alpha-adrenergic receptors and beta-adrenergic receptors respectively. (S)-1-Methylnicotinium iodide has been shown to have depressor effects on the central nervous system, although this effect may be limited by its rapid metabolism by demethylation into (R)-1-methylnicotinium iodide.

Formula: C₁₁H₁₇N₂I

Purity: Min. 95%

Molecular weight: 304.17 g/mol

Ref: 3D-FM25894