CAS 214491-43-7

6,8-Difluoro-4-methylumbelliferyl phosphate

Description:

6,8-Difluoro-4-methylumbelliferyl phosphate is a synthetic chemical compound primarily used as a substrate in biochemical assays, particularly for the detection of phosphatase activity. This compound features a fluorinated umbelliferone structure, which enhances its fluorescent properties, making it useful in various analytical applications. The presence of two fluorine atoms at the 6 and 8 positions of the umbelliferyl moiety increases the compound's stability and alters its electronic properties, contributing to its fluorescence characteristics. The phosphate group is crucial for its reactivity, allowing it to be hydrolyzed by phosphatases, resulting in the release of the fluorescent umbelliferone, which can be quantitatively measured. This compound is often utilized in molecular biology and biochemistry for enzyme assays, providing a sensitive and specific method for studying enzyme kinetics and activity. Safety data sheets should be consulted for handling and storage guidelines, as with any chemical substance, to ensure proper laboratory practices.

Formula: C₁₀H₇F₂O₆P

InChI: InChI=1S/C10H7F2O6P/c1-4-2-7(13)17-9-5(4)3-6(11)10(8(9)12)18-19(14,15)16/h2-3H,1H3,(H2,14,15,16)

InChI key: InChIKey=DZANYXOTJVLAEE-UHFFFAOYSA-N

SMILES: FC1=C2C(=CC(F)=C1OP(=O)(O)O)C(C)=CC(=O)O2

Synonyms:

• DiFMUP
• 2H-1-Benzopyran-2-one, 6,8-difluoro-4-methyl-7-(phosphonooxy)-
• 6,8-Difluoro-4-methyl-7-(phosphonooxy)-2H-1-benzopyran-2-one
• 6,8-Difluoro-4-methylumbelliferyl phosphate

6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE

CAS: 214491-43-7

Formula: C₁₀H₇F₂O₆P

Purity: 98%

Molecular weight: 292.1295

Ref: IN-DA00C1OV

DiFMUP

CAS: 214491-43-7

DiFMUP

Purity: 98%

Molecular weight: 292.13g/mol

Ref: 54-PC111732

DiFMUP

CAS: 214491-43-7

DiFMUP (6,8-Difluoro-4-methylumbelliferyl phosphate) inhibits protein tyrosine phosphatases (PTPs) and can be used to assay threonine phosphatase activity.

Formula: C₁₀H₇F₂O₆P

Purity: 99.25% - >99.99%

Color and Shape: Solid

Molecular weight: 292.13

Ref: TM-T31458

6,8-Difluoro-Hymecromone Phosphate

CAS: 214491-43-7

Formula: C₁₀H₇F₂O₆P

Molecular weight: 292.13

Ref: 4Z-H-092006