CAS 21462-39-5

Clindamycin hydrochloride

Description:

Clindamycin hydrochloride is an antibiotic belonging to the lincosamide class, primarily used to treat various bacterial infections, particularly those caused by anaerobic bacteria and certain protozoa. It is effective against skin infections, respiratory tract infections, and some types of bone infections. The substance appears as a white to off-white crystalline powder, which is soluble in water and methanol but has limited solubility in organic solvents. Its chemical formula is C18H20ClN2O2S, and it has a molecular weight of approximately 343.88 g/mol. Clindamycin hydrochloride works by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of bacteria. It is often administered orally or intravenously, depending on the severity of the infection. Side effects may include gastrointestinal disturbances, such as diarrhea, and in rare cases, it can lead to Clostridium difficile-associated diarrhea. Due to its mechanism of action and spectrum of activity, clindamycin is a valuable option in treating infections where penicillin is ineffective or contraindicated.

Formula: C₁₈H₃₄Cl₂N₂O₅S

InChI: InChI=1/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9?,10-,11+,12?,13+,14-,15-,16-,18-;/m0./s1

InChI key: InChIKey=AUODDLQVRAJAJM-XJQDNNTCSA-N

SMILES: [C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)([C@H](C)Cl)[C@]2(O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)[H].Cl

Synonyms:

• (2R,4S)-N-[2-chloro-1-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl]propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide hydrochloride
• 7(S)-Chloro-7-deoxylincomycin hydrochloride
• 7-Chloro-7-deoxylincomycin hydrochloride
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</smallcap>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-<smallcap>L</span>-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, trans- α-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, monohydrochloride, (2S-trans)-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1)
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride
• Antirobe vet.
• Cleocin hydrochloride
• ClidamycinHydrochloride
• Clinacin
• Clindamycin HCl
• Clindavet
• Clindimycin hydrochloride
• Clindomycin hydrochloride
• Dalacina
• methyl 7-chloro-6,7,8-trideoxy-6-({[(2R)-1-methyl-4-propylpyrrolidinium-2-yl]carbonyl}amino)-1-thio-beta-L-erythro-octopyranoside chloride
• methyl 7-chloro-6,7,8-trideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-L-threo-alpha-D-galacto-octopyranoside hydrochloride (1:1)
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, monohydrochloride, (2S-trans)-
• Clindamycin hydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1)
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, trans- α-
• (7S)-7-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE
• clindomycinhydrochloride
• Lujiemycin
• CLINDAMYCINHYDROCHLORIDE,CRYSTAL
• L-threo-.alpha.-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(2S,4R)-1-methyl-4-propyl-2-pyrrolidinylcarbonylamino-1-thio-, monohydrochloride
• clindimycinhydrochloride
• Clindaymcin Hydrochloride BP98,USP25,EP97
• 7(S)-CHLORO-7-DEOXYLINCOMYCIN HCL
• 7-chloro-7-deoxylincomycinhydrochloride
• monohydrochloride,(2s-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio
• CLEOCIN
• (2S-TRANS)-METHYL 7-CHLORO-6,7,8-TRIDEOXY-6[[(1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL]AMINO]-1-THIO-L-THREO-ALPHA-D-GALACTO-OCTOPYRANOSIDE
• 7(S)-CHLORO-7-DEOXYLINCOMYCIN
• CLINDAMYCIN HC

Clindamycin Hydrochloride Monohydrate

CAS: 18323-44-9, 21462-39-5, 58207-19-5

Formula: C₁₈H₃₃ClN₂O₅S·HCl·H₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 479.46

Ref: 3B-C2256

Clindamycin Hydrochloride

CAS: 21462-39-5

Color and Shape: Neat

Ref: 61-FOR0259.00

CLINDAMYCIN HYDROCHLORIDE RS

CAS: 21462-39-5

CLINDAMYCIN HYDROCHLORIDE RS

Ref: 41-ICRS46473

CLINDAMYCIN HYDROCHLORIDE CRS

CAS: 21462-39-5

CLINDAMYCIN HYDROCHLORIDE CRS

Formula: C₁₈H₃₄Cl₂N₂O₅S

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 461.444

Ref: 41-C2250000

(7S)-7-Chloro-7-deoxylincomycin hydrochloride

CAS: 21462-39-5

Formula: C₁₈H₃₄Cl₂N₂O₅S

Purity: 95%

Color and Shape: Solid

Molecular weight: 461.4440

Ref: IN-DA003P0L

Clindamycin HCl (Clindamycin Phosphate EP Impurity E HCl)

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 424.99 36.46

Ref: 4Z-C-5071

Clindamycin hydrochloride

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅S·HCl·xH₂O

Purity: ≥ 800μg/mg (C18H33ClN2O5S, as is)

Color and Shape: White to off-white powder

Molecular weight: 461.44 (anhydrous)

Ref: 7W-GA5034

Clindamycin hydrochloride

CAS: 21462-39-5

Clindamycin hydrochloride

Purity: ≥98%

Molecular weight: 461.44g/mol

Ref: 54-BUP14814

Clindamycin hydrochloride

CAS: 21462-39-5

Clindamycin hydrochloride

Formula: C₁₈H₃₃ClN₂O₅S·ClH

Purity: 94% (q-nmr) (calculated (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 461.44395g/mol

Ref: 54-BIC0117

Clindamycin Hydrochloride

CAS: 21462-39-5

Color and Shape: Neat

Ref: 86-MM0259.00

Clindamycin 1000 µg/mL in Acetonitrile

Controlled Product

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅S·ClH

Color and Shape: Single Solution

Molecular weight: 461.44

Ref: 04-A11670090AL-1000

Clindamycin hydrochloride

Controlled Product

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅S·ClH

Color and Shape: Neat

Molecular weight: 461.44

Ref: 04-C11670100

Clindamycin hydrochloride

CAS: 21462-39-5

Clindamycin hydrochloride (Clinimycin HCl) inhibits protein synthesis by acting on the 50S ribosomal. Clindamycin is a chlorinated broad-spectrum antibiotic.

Formula: C₁₈H₃₃ClN₂O₅S·HCl

Purity: 99.80%

Color and Shape: White Crystalline Powder

Molecular weight: 461.44

Ref: TM-T6448

Clindamycin Hydrochloride

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅SHCl

Molecular weight: 425.0 : 36.5

Ref: ST-EA-CP-C26021

Clindamycin Hydrochloride

CAS: 21462-39-5

Impurity Clindamycin Phosphate EP Impurity E
Stability Hygroscopic
Applications Clindamycin Hydrochloride (Clindamycin Phosphate EP Impurity E) is a semi-synthetic antibiotic prepared from Lincomycin. Antibacterial.
References Birkenmeyer, R.D., et al.: J. Med. Chem., 13, 616 (1970); Oesterling, et al.: J. Pharm. Sci., 59, 63 (1970); Gray, J.E., et al.: Toxicol. Appl. Pharmacol., 21, 516 (1972); Brown, L.W., et al.: Anal. Profiles Drug Subs., 10, 75 (1981);

Formula: C₁₈H₃₃ClN₂O₅S·ClH

Color and Shape: White To Off-White

Molecular weight: 461.44

Ref: TR-C580000

Clindamycin hydrochloride

CAS: 21462-39-5

Inhibitor of protein synthesis; lincosamide class

Formula: C₁₈H₃₄Cl₂N₂O₅S

Color and Shape: White Powder

Molecular weight: 461.44 g/mol

Ref: 3D-AC07735

Clindamycin hydrochloride - 94%

CAS: 21462-39-5

Clindamycin hydrochloride - 94% is an antibiotic that belongs to the lincosamide class of antibiotics, derived from the bacterium Streptomyces lincolnensis. This compound functions predominantly as a bacterial protein synthesis inhibitor, exerting its effects by binding to the 50S subunit of the bacterial ribosome. This binding action disrupts the process of peptide chain elongation, thereby impeding the growth and proliferation of susceptible bacteria.

Formula: C₁₈H₃₃ClN₂O₅S·HCl

Color and Shape: Powder

Molecular weight: 461.44 g/mol

Ref: 3D-AC178993

Clindamycin (hydrochloride)

CAS: 21462-39-5

Purity: 98%

Molecular weight: 460.16

Ref: 10-F554440

Cis-Clindamycin Hydrochloride

Controlled Product

CAS: 21462-39-5

Formula: C₁₈H₃₃ClN₂O₅S·ClH

Color and Shape: Neat

Molecular weight: 460.15655

Ref: TR-C580080