CAS 21466-01-3

[(2R,3R,4S,5R)-5-(6-amino-2-chloro-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

Description:

The chemical substance with the name "[(2R,3R,4S,5R)-5-(6-amino-2-chloro-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate" and CAS number 21466-01-3 is a nucleotide analog. It features a tetrahydrofuran ring that is substituted with hydroxyl groups, contributing to its potential biological activity. The presence of a 6-amino-2-chloropurine moiety suggests that it may interact with nucleic acid synthesis pathways, potentially acting as an antiviral or anticancer agent. The dihydrogen phosphate group indicates that it can participate in phosphorylation reactions, which are crucial in cellular signaling and metabolism. This compound's stereochemistry, denoted by the (2R,3R,4S,5R) configuration, is significant for its biological interactions, as the three-dimensional arrangement of atoms can influence its binding affinity to biological targets. Overall, this compound's unique structural features position it as a candidate for further research in medicinal chemistry and pharmacology.

Formula: C₁₀H₁₃ClN₅O₇P

InChI: InChI=1/C10H13ClN5O7P/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,14,15)(H2,19,20,21)/t3-,5+,6+,9-/m1/s1

2-Chloroadenosine 5''-monophosphate triethylamine salt

CAS: 21466-01-3

Ref: 7W-GN5067

2-Chloroadenosine 5'-monophosphate triethylamine salt

CAS: 21466-01-3

2-Chloroadenosine 5'-monophosphate triethylamine salt is a phosphoramidite that has anticancer and antiviral activities. It is synthesized by reacting 2-chloroadenosine with triethylamine. This product has a novel chemical structure and it can be used as an activator for the synthesis of modified DNA, RNA, and other nucleosides. It is also used in the manufacture of deoxyribonucleosides, ribonucleosides, and other nucleotides.

Formula: C₁₀H₁₃ClN₅O₇P·C₁₂H₃₀N₂

Purity: Min. 95%

Molecular weight: 584.05 g/mol

Ref: 3D-NC10383