CAS 2147701-33-3

I-CBP112 hydrochloride

CAS: 2147701-33-3

I-CBP112 hydrochloride

Purity: ≥95%

Molecular weight: 505.05g/mol

Ref: 54-BUP05062

I-CBP112 hydrochloride

CAS: 2147701-33-3

I-CBP112 selectively inhibits CBP/p300 bromodomains, with minimal effect on others, and reduces leukemia cell growth, enhancing JQ1 and doxorubicin's effects.

Formula: C₂₇H₃₇ClN₂O₅

Purity: 99.69%

Color and Shape: Solid

Molecular weight: 505.05

Ref: TM-T4247

I-Cbp 112 hydrochloride

CAS: 2147701-33-3

I-Cbp 112 hydrochloride is a small molecule inhibitor that is synthetically derived. Its primary mode of action involves the selective inhibition of bromodomain-containing proteins, specifically targeting interactions between bromodomains and acetylated lysine residues on histone tails. This results in modulation of transcriptional regulation by interfering with the reader functions of bromodomains, thereby impacting chromatin remodeling and gene expression pathways.

Formula: C₂₇H₃₇ClN₂O₅

Purity: Min. 95%

Molecular weight: 505 g/mol

Ref: 3D-XKD70133