CAS 2149-79-3
:5-Bromo-5′-uridylic acid
Description:
5-Bromo-5′-uridylic acid, also known as 5-bromo-uridine monophosphate, is a nucleotide analog characterized by the presence of a bromine atom at the 5-position of the uracil base. This compound is a derivative of uridine monophosphate (UMP) and is involved in various biochemical processes, particularly in the study of RNA synthesis and function. It exhibits properties typical of nucleotides, including the ability to participate in hydrogen bonding and base pairing due to its pyrimidine structure. The bromine substitution can influence its biological activity and interactions with enzymes, making it a useful tool in molecular biology and pharmacology. Additionally, 5-bromo-5′-uridylic acid can be utilized in research related to antiviral agents and as a potential therapeutic compound. Its solubility in water and stability under physiological conditions make it suitable for various experimental applications. As with many nucleotides, it is important to handle this compound with care, considering its potential biological effects and reactivity.
Formula:C9H12BrN2O9P
InChI:InChI=1S/C9H12BrN2O9P/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(21-8)2-20-22(17,18)19/h1,4-6,8,13-14H,2H2,(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1
InChI key:InChIKey=IDPVUMJNEZFMNU-UAKXSSHOSA-N
SMILES:O[C@H]1[C@@H](O[C@H](COP(=O)(O)O)[C@H]1O)N2C(=O)NC(=O)C(Br)=C2
Synonyms:- 5-Bromo-5′-uridylic acid
- 5-Bromo-Uridine-5'-monophosphate
- 5-Bromo-Uridine-5'-monophosphate,disodium salt
- 5-Bromouridine monophosphate
- 5-Bromouridine-5'-Monophosphate
- 5′-Uridylic acid, 5-bromo-
- Uridine, 5-bromo-, 5′-(dihydrogen phosphate)
- Uridine, 5-bromo-, 5′-phosphate
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Found 1 products.
5-Bromouridine-5'-monophosphate
CAS:<p>5-Bromouridine-5'-monophosphate is a nucleoside analog of uridine. It is an antiviral and antineoplastic agent that inhibits the synthesis of DNA by inhibiting the enzyme ribonucleotide reductase. This enzyme catalyzes the conversion of ribonucleosides to diphosphates, which are precursors for DNA and RNA synthesis. 5-Bromouridine-5'-monophosphate has been shown to be effective against some cancer cells in vitro and in vivo, but has not been tested on humans.</p>Formula:C9H12BrN2O9PPurity:Min. 95%Molecular weight:403.08 g/mol
