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CAS 2149-82-8

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Orotidine 5′-monophosphate

Description:
Orotidine 5′-monophosphate (OMP) is a pyrimidine nucleotide that plays a crucial role in the biosynthesis of nucleic acids. It is a key intermediate in the de novo synthesis pathway of pyrimidine nucleotides, which are essential for DNA and RNA synthesis. OMP is characterized by its structure, which includes a pyrimidine ring, a ribose sugar, and a phosphate group. The compound is typically found in its monophosphate form, which is vital for its biological functions. OMP is involved in the conversion to uridine monophosphate (UMP) through the action of the enzyme OMP decarboxylase. This transformation is a significant step in the synthesis of RNA and DNA precursors. Orotidine 5′-monophosphate is soluble in water and exhibits stability under physiological conditions, making it an important molecule in cellular metabolism. Its CAS number, 2149-82-8, is used for identification in chemical databases and regulatory contexts. Overall, OMP is integral to cellular processes, particularly in the context of nucleotide metabolism and genetic information transfer.
Formula:C10H13N2O11P
InChI:InChI=1S/C10H13N2O11P/c13-5-1-3(9(16)17)12(10(18)11-5)8-7(15)6(14)4(23-8)2-22-24(19,20)21/h1,4,6-8,14-15H,2H2,(H,16,17)(H,11,13,18)(H2,19,20,21)/t4-,6-,7-,8-/m1/s1
InChI key:InChIKey=KYOBSHFOBAOFBF-XVFCMESISA-N
SMILES:O[C@H]1[C@@H](O[C@H](COP(=O)(O)O)[C@H]1O)N2C(C(O)=O)=CC(=O)NC2=O
Synonyms:
  • 1,2,3,6-Tetrahydro-2,6-dioxo-3-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-4-pyrimidinecarboxylic acid
  • 2,6-Dioxo-3-(5-O-phosphonopentofuranosyl)-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid
  • 3-{3,4-Dihydroxy-5-[(phosphonooxy)methyl]tetrahydro-2-furanyl}-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidincarbons?ure
  • 3-{3,4-Dihydroxy-5-[(phosphonooxy)methyl]tetrahydro-2-furanyl}-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid
  • 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-
  • 4-pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-(5-O-phosphonopentofuranosyl)-
  • 5′-Omp
  • Acide 3-{3,4-dihydroxy-5-[(phosphonooxy)méthyl]tétrahydro-2-furanyl}-2,6-dioxo-1,2,3,6-tétrahydro-4-pyrimidinecarboxylique
  • OMP (nucleotide)
  • Ometoprim
  • See more synonyms
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